Evidence map›Paper›PMID 32523574›Full record

ArticleFrontiers in microbiology2020

Combination of Antifungal Drugs and Protease Inhibitors Prevent

Matthew B Lohse, Megha Gulati, Charles S Craik, Alexander D Johnson, Clarissa J Nobile

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
0.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Secretion of serine proteases by planktonic- and biofilm-growing cells of Candida parapsilosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Bixin fromACS omega · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Secreted Aspartic Proteinases: Key Factors inInternational journal of molecular sciences · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matthew B LohseDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, United States.
Megha GulatiDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
Charles S CraikDepartment of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, United States.
Alexander D JohnsonDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, United States.
Clarissa J NobileDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.
University of California, San Francisco · USUniversity of California, Merced · US

Funding

X-ray Screening and Rapid Structure DeterminationP50AI150476 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EMERMAN, MICHAEL · 2019 to 2021
$14.4M
The transcriptional circuitry controlling biofilm development in Candida albicansR01AI083311 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, ALEXANDER D · 2011 to 2020
$4.3M
Genetic regulation of inter- and intra-species microbial community formationR35GM124594 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI NOBILE, CLARISSA JANE · 2017 to 2021
$2.0M
Development of Novel Protease Activity-Based Diagnostics for the Rapid Identification of Candida InfectionsR43AI131710 · NIAID · BIOSYNESIS, INC. · PI LOHSE, MATTHEW B. · 2017 to 2018
$596k
Development of Therapeutics to Treat Candida albicans Biofilm InfectionsR41AI112038 · NIAID · BIOSYNESIS, INC. · PI NOBILE, CLARISSA JANE · 2015 to 2015
$225k
NIAID NIH HHS P50 AI150476NIAID NIH HHS R01 AI083311NIAID NIH HHS R41 AI112038NIAID NIH HHS R43 AI131710NIGMS NIH HHS R35 GM124594
6 · The paper itself

Abstract

Biofilms formed by the fungal pathogen

Indexed as

antimicrobial resistanceaspartyl protease inhibitorsbiofilmsCandida albicansprotease inhibitorstherapeutics

Identifiers

PMID32523574
PMCPMC7261846
OpenAlexW3032806542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.