ReviewFrontiers in aging neuroscience2020
The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study.
Review in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Effect of acupuncture on ischemic stroke patients with hypertension: a randomized clinical trail.Frontiers in neurologyTrial
- Clinical characteristics of acupoint sensitization in patients with essential hypertension: a cross-sectional matched case-control study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- From peripheral initiation to central integration: a narrative review of the antihypertensive mechanisms of acupuncture in regulating autonomic nervous system homeostasis.Frontiers in neuroscience · 2026Review
- Electroacupuncture ameliorates chronic heart failure: the role of CRH neurons in the paraventricularnucleus of the hypothalamus.Frontiers in neuroscience · 2026Article
- The Effect of Electroacupuncture on Microcirculation in Patients With Hypertension and Cognitive Impairment: Protocol for a Multicenter Randomized Controlled Trial.JMIR research protocols · 2025Article
- A Clinical Study on the Efficacy of Acupuncture Treatment in Essential Hypertension: Protocol for Randomized Controlled Trial.JMIR research protocols · 2025Article
- The Autonomic Nervous System in Acupuncture for Gastrointestinal Dysmotility: From Anatomical Insights to Clinical Medicine.International journal of medical sciences · 2025Review
- Prediction of acupuncture efficacy in acute ischemic stroke constructing a clinical-radiomics multimodal model.Frontiers in neurology · 2025Article
- Acupuncture for Essential Hypertension and Endothelial Dysfunction: A Randomized Clinical Trial.Arquivos brasileiros de cardiologia · 2025Article
- Review
- Electroacupuncture pretreatment mediates sympathetic nerves to alleviate myocardial ischemia-reperfusion injury via CRH neurons in the paraventricular nucleus of the hypothalamus.Chinese medicine · 2024Article
- Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome.Frontiers in neuroscience · 2024Review
- Research trends of acupuncture therapy for hypertension over the past two decades: a bibliometric analysis.Cardiovascular diagnosis and therapy · 2023Review
- Electroacupuncture relieves portal hypertension by improving vascular angiogenesis and linking gut microbiota in bile duct ligation rats.Frontiers in microbiology · 2023Article
- Sympathoinhibitory electroacupuncture (EA) interacts positively with anti-inflammatory EA alleviating blood pressure in hypertensive rats.Frontiers in cardiovascular medicine · 2023Article
- A Biophysical Model for Cardiovascular Effects of Acupuncture-Underlying Mechanisms Based on First Principles.Medical acupuncture · 2022Review
- Low-energy Pulsed Electromagnetic Field Therapy Reduces Pain in Fibromyalgia: A Randomized Single-blind Controlled Pilot Study.Rheumatology and immunology research · 2022Article
- Involvement of Neuropeptide Y within Paraventricular Nucleus in Electroacupuncture Inhibiting Sympathetic Activities in Hypertensive Rats.International journal of hypertension · 2022Article
- Acupuncture for hypertension with insomnia: Study protocol for a randomized, sham-controlled, subject-and-assessor-blinded trial.Frontiers in psychiatry · 2022Article
- The application of acupuncture in cardiopathy: A bibliometric analysis based on Web of Science across ten recent years.Frontiers in cardiovascular medicine · 2022Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a component of traditional Chinese medicine (TCM), acupuncture has the potential to lower blood pressure (BP) in patients with hypertension. Emerging evidence indicates that the acupuncture-induced inhibition of high BP occurs through the activation of the pathway in the afferent, central, and efferent pathways. An increasing number of studies have demonstrated that acupuncture not only activates distinct brain regions under conditions of hypertension caused by an imbalance between the sympathetic and parasympathetic systems but also modulates neurotransmitters in related brain regions to alleviate the autonomic response. The activity of these pathways can be assessed by injecting agonists or inhibitors or by performing neurotomy. This review focuses on the clinical and mechanistic studies of acupuncture in modulating BP, which might provide a neurobiological foundation for the effects of acupuncture. Although many mechanisms underlying the effects of acupuncture on cardiovascular function have been identified, further investigation is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.