Evidence map›Paper›PMID 32523339›Full record

ArticleInternational journal of nanomedicine2020

Comparative Study of Antibacterial Effects of Titanium Dioxide Nanoparticles Alone and in Combination with Antibiotics on MDR

Fatma Y Ahmed, Usama Farghaly Aly, Rehab M Abd El-Baky, Nancy G F M Waly

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 55 citations in OpenAlex.

  1. Eco-friendly Cu-TiOAMB Express · 2026
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  10. Review of Antimicrobial Properties of Titanium Dioxide Nanoparticles.International journal of molecular sciences · 2024
    Review
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  12. Article
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  15. Review
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  19. Antimicrobial Resistance and Inorganic Nanoparticles.International journal of molecular sciences · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fatma Y AhmedDepartment of Microbiology and Immunology, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Usama Farghaly AlyDepartment of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Rehab M Abd El-BakyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Nancy G F M WalyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Minia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe efficacy of several antimicrobial agents has been hindered due to the increasing frequency of multidrug-resistant (MDR) PURPOSE: This study aims to investigate the prevalence of MDR MATERIALS AND

methodsThe synthesis of TDN by the sol-gel method was carried out. Particle size measurements and morphology were done using dynamic light scattering (DLS) and high-resolution transmission electron microscopy (HR-TEM). To investigate the physical and chemical changes of drugs due to the combination, the tested drugs, both alone and in combination with TDN, were subjected to differential scanning calorimetry (DSC), infrared (IR) spectroscopy, and X-ray diffraction studies. Antimicrobial susceptibility was detected by agar disc-diffusion assay. The minimum inhibitory concentration (MIC) of TDN and the tested antibiotics were assessed by the agar dilution method. Checkerboard analysis was performed to determine the combined effect of TDN and the tested antibiotics against 25 MDR

resultsTDNs were prepared with an average particle size of 64.77 ± 0.14 nm with an accepted polydispersity index (PDI) value of 0.274 ± 0.004. TEM showed that the particles were shaped into irregular spheres. Twenty-five

conclusionUsing TDN in combination with antibiotics can help in the treatment of MDR

Indexed as

Anti-Bacterial AgentsCalorimetryCiprofloxacinDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsNanoparticlesParticle SizePseudomonas aeruginosaPseudomonas InfectionsSpectroscopy, Fourier Transform InfraredTitaniumX-Ray DiffractionAnti-Bacterial AgentsCiprofloxacinTitaniumtitanium dioxidecheckerboard assayMDR P. aeruginosatitanium dioxide nanoparticle

Identifiers

PMID32523339
PMCPMC7236244
OpenAlexW3025889791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.