Evidence map›Paper›PMID 32523060›Full record

ArticleScientific reports2020

Reference Genes for Expression Studies in Human CD8

Marco Geigges, Patrick M Gubser, Gunhild Unterstab, Yannic Lecoultre, Renato Paro, Christoph Hess

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Biomedicines · 2024
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  8. Article
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  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco Geigges *Epigenomics Group, Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.ORCID http://orcid.org/0000-0001-9071-5162
Patrick M Gubser *Immunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
Gunhild UnterstabImmunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
Yannic LecoultreImmunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland.
Renato ParoEpigenomics Group, Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. renato.paro@bsse.ethz.ch.ORCID http://orcid.org/0000-0003-3308-2965
Christoph HessImmunobiology Laboratory, Department of Biomedicine, University and University Hospital of Basel, Basel, Switzerland. christoph.hess@usb.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is widely used for mRNA quantification. To accurately measure changing gene transcript levels under different experimental conditions, the use of appropriate reference gene transcripts is instrumental. In T cell immunology, suitable reference genes have been reported for bulk CD4

Indexed as

AdolescentAdultCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleGene Expression ProfilingHumansImmunologic MemoryInterferon-gammaMaleReal-Time Polymerase Chain ReactionReference StandardsRestRNA, MessengerYoung AdultInterferon-gammaRNA, Messenger

Identifiers

PMID32523060
PMCPMC7286888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.