Evidence map›Paper›PMID 32522869›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Stimuli-responsive composite biopolymer actuators with selective spatial deformation behavior.

Yushu Wang, Wenwen Huang, Yu Wang, Xuan Mu, Shengjie Ling, Haipeng Yu, Wenshuai Chen, Chengchen Guo, Matthew C Watson, Yingjie Yu and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Pollen-inspired biopolymer-based multifunctional films.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Biopolymer Membranes for Osmotic Power Generation in Bionic Applications.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Bioinspired Stimuli-Responsive Materials for Soft Actuators.Biomimetics (Basel, Switzerland) · 2024
    Review
  11. Review
  12. Review
  13. Bio-Inspired Multiscale Design for Strong and Tough Biological Ionogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  14. Review
  15. Synthetic growth by self-lubricated photopolymerization and extrusion inspired by plants and fungi.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Soft actuators for real-world applications.Nature reviews. Materials · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yushu WangDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.ORCID 0000-0002-3136-2691
Wenwen HuangDepartment of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-8175-9083
Yu WangDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.ORCID 0000-0003-0249-4414
Xuan MuDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.
Shengjie LingSchool of Physical Science and Technology, Shanghai Tech University, Shanghai 201210, China.ORCID 0000-0003-1156-0479
Haipeng YuKey laboratory of Bio-based Material Science and Technology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.ORCID 0000-0003-0634-7913
Wenshuai ChenKey laboratory of Bio-based Material Science and Technology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
Chengchen GuoDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.ORCID 0000-0001-9253-3469
Matthew C WatsonDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.ORCID 0000-0002-5101-5697
Yingjie YuDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.
Lauren D BlackDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.ORCID 0000-0002-7486-5811
Meng LiDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.
Fiorenzo G OmenettoDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155.
Chunmei LiDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155; chunmei.li@tufts.edu david.kaplan@tufts.edu.ORCID 0000-0002-5666-8435
David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155; chunmei.li@tufts.edu david.kaplan@tufts.edu.ORCID 0000-0002-9245-7774

Funding

Translational Bioreactors - Engineering Complex TissuesP41EB002520 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2004 to 2018
$16.7M
Tissue Engineering Resource Center: TTDP41EB027062 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gordana Vunjak-Novakovic · 2019 to 2026
$12.6M
Models to Predict Protein Biomaterial PerformanceU01EB014976 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI BUEHLER, MARKUS J., KAPLAN, DAVID L. · 2012 to 2020
$5.2M
NIBIB NIH HHS P41 EB002520NIBIB NIH HHS P41 EB027062NIBIB NIH HHS U01 EB014976
6 · The paper itself

Abstract

Bioinspired actuators with stimuli-responsive and deformable properties are being pursued in fields such as artificial tissues, medical devices and diagnostics, and intelligent biosensors. These applications require that actuator systems have biocompatibility, controlled deformability, biodegradability, mechanical durability, and stable reversibility. Herein, we report a bionic actuator system consisting of stimuli-responsive genetically engineered silk-elastin-like protein (SELP) hydrogels and wood-derived cellulose nanofibers (CNFs), which respond to temperature and ionic strength underwater by ecofriendly methods. Programmed site-selective actuation can be predicted and folded into three-dimensional (3D) origami-like shapes. The reversible deformation performance of the SELP/CNF actuators was quantified, and complex spatial transformations of multilayer actuators were demonstrated, including a biomimetic flower design with selective petal movements. Such actuators consisting entirely of biocompatible and biodegradable materials will offer an option toward constructing stimuli-responsive systems for in vivo biomedicine soft robotics and bionic research.

Indexed as

Biocompatible MaterialsBiomimetic MaterialsBionicsCelluloseElastinHydrogelsMolecular ConformationNanofibersProtein EngineeringRoboticsSilkBiocompatible MaterialsCelluloseElastinHydrogelsSilkactuationbionicbiopolymersreversiblestimuli responsive

Identifiers

PMID32522869
PMCPMC7322001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.