ArticleJournal of clinical microbiology2020
Population Genomic Molecular Epidemiological Study of Macrolide-Resistant Streptococcus pyogenes in Iceland, 1995 to 2016: Identification of a Large Clonal Population with a
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In one paragraph
Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Global trends in macrolide and lincosamide resistance in Streptococcus species: a comprehensive systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Inhibitors of GapN-dependent NADPH supply as potential lead compounds for novel therapeutics againstVirulence · 2026Article
- Identification ofAntimicrobial agents and chemotherapy · 2026Article
- Increase of macrolide resistance amongAntimicrobial agents and chemotherapy · 2025Article
- Rare emm6.10Microorganisms · 2025Article
- ICESp1109, a Novel Hybrid Integrative Conjugative Element of Macrolide-Resistant Streptococcus pyogenes Serotype M77 Collected Between 2003 and 2017 in Poland.The Journal of infectious diseases · 2025Article
- Global spread of Streptococcus pyogenes A genomics-supported narrative review.FEMS microbiology reviews · 2025Review
- Review
- [Research progress on the mechanism of -lactam resistance in group AZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Review
- Streptococcus pyogenes Φ1207.3 Is a Temperate Bacteriophage Carrying the Macrolide Resistance Gene PairMicrobiology spectrum · 2023Article
- A review of penicillin binding protein and group AFrontiers in cellular and infection microbiology · 2023Review
- Genome-Wide Transposon Mutagenesis Screens Identify Group A Streptococcus Genes Affecting Susceptibility to β-Lactam Antibiotics.Journal of bacteriology · 2022Article
- A Chimeric Penicillin Binding Protein 2X Significantly Decreases in Vitro Beta-Lactam Susceptibility and Increases in Vivo Fitness of Streptococcus pyogenes.The American journal of pathology · 2022Article
- Invasive Group A Streptococcal Penicillin Binding Protein 2× Variants Associated with Reduced Susceptibility to β-Lactam Antibiotics in the United States, 2015-2021.Antimicrobial agents and chemotherapy · 2022Article
- Article
- Editorial: Streptococci in infectious diseases - pathogenic mechanisms and host immune responses.Frontiers in microbiology · 2022Article
- The Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target inFrontiers in microbiology · 2022Article
- Isolation of Group A Streptococci with ReducedAntimicrobial agents and chemotherapy · 2021Article
- Review
- Determination of Lekethromycin, a Novel Macrolide Lactone, in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study.Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Sara B Southon *Department of Clinical Microbiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.
Stephen B Beres *Center for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0003-3041-0185
Priyanka KachrooCenter for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0002-3563-7832
Matthew Ojeda SaavedraCenter for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Helga ErlendsdóttirDepartment of Clinical Microbiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.
Gunnsteinn HaraldssonDepartment of Clinical Microbiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.ORCID 0000-0002-9897-0384
Prasanti YerramilliCenter for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Layne PruittCenter for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Luchang ZhuCenter for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
James M MusserCenter for Molecular and Translational Human Infectious Disease Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.
Karl G KristinssonDepartment of Clinical Microbiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland karl@landspitali.is.
Houston Methodist · USUniversity of Iceland · ISNational University Hospital of Iceland · IS
Funding
Determinants of Streptococcus pyogenes virulence in the primate oropharynx: A genome-wide analysisR21AI139369 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI MUSSER, JAMES MALLORY · 2019 to 2020
$444kDeterminants of Streptococcus pyogenes fitness in the female primate genital tract: A genome-wide analysisR21AI146771 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI MUSSER, JAMES MALLORY · 2019 to 2020
$444kNIAID NIH HHS R21 AI139369NIAID NIH HHS R21 AI146771
Abstract
Resistance to macrolide antibiotics is a global concern in the treatment of
Indexed as
Streptococcal InfectionsStreptococcus pyogenesAnti-Bacterial Agentsbeta-LactamsDrug Resistance, BacterialEpidemiologic StudiesGenotypeHumansIcelandMacrolidesMetagenomicsMicrobial Sensitivity TestsMutationAnti-Bacterial Agentsbeta-LactamsMacrolidesantibiotic resistancebeta-lactamsmacrolidesmolecular epidemiologypopulation genomicsStreptococcus pyogeneswhole-genome sequencing
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What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.