ArticleBMJ open gastroenterology2020
Pneumatosis intestinalis in COVID-19.
Article in BMJ open gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A Systematic Review of Abdominal Imaging Findings in COVID-19 Patients.Visceral medicine · 2021Pooled it
- Article
- Pneumatosis Intestinalis and Concurrent Focal Diaphragmatic Pneumatosis Cystoides Presenting With Pneumoperitoneum in a 20 Year-Old Male: A Case Report.Clinical case reports · 2025Article
- Acute lymphoblastic leukemia with pneumatosis cystoides intestinalis after hematopoietic stem cell transplantation: a case report.The Journal of international medical research · 2024Article
- The Challenge of Pneumatosis Intestinalis: A Contemporary Systematic Review.Journal of personalized medicine · 2024Review
- The spectrum of pneumatosis intestinalis in the adult. A surgical dilemma.World journal of gastrointestinal surgery · 2023Review
- SARS-CoV-2 and gastrointestinal diseases.Frontiers in microbiology · 2023Review
- Direct, indirect, post-infection damages induced by coronavirus in the human body: an overview.Virusdisease · 2022Review
- Intra-Amniotic Administration-An Emerging Method to Investigate Necrotizing Enterocolitis, In Vivo (Nutrients · 2022Article
- Findings of Abdominal Imaging in Patients with COVID-19 - Part 1: Hollow Organs.Middle East journal of digestive diseases · 2022Review
- Article
- Article
- Acute mesenteric ischemia in COVID-19: Case report and current understanding.Qatar medical journal · 2022Article
- GASTROINTESTINAL COMPLICATIONS OF CORONAVIRUS DISEASE (COVID-19).Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022Review
- Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children.Clinical imaging · 2021Review
- Applications of laboratory findings in the prevention, diagnosis, treatment, and monitoring of COVID-19.Signal transduction and targeted therapy · 2021Review
- Acute oesophageal necrosis in a patient with recent SARS-CoV-2.BMJ case reports · 2021Article
- What the dental practitioner needs to know about pharmaco-therapeutic modalities of COVID-19 treatment: A review.Journal of dental sciences · 2021Review
- Biomedical Text Link Prediction for Drug Discovery: A Case Study with COVID-19.Pharmaceutics · 2021Article
- Gastrointestinal perforation secondary to COVID-19: Case reports and literature review.Medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCOVID-19 is a respiratory illness due to novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), described in December 2019 in Wuhan (China) and rapidly evolved into a pandemic. Gastrointestinal (GI) tract can also be involved. CASE PRESENTATION: A 44-year-old man was hospitalised for COVID-19-associated pneumonia. A rapid recovery of respiratory and general symptoms was observed after 1 week of treatment with lopinavir/ritonavir plus hydroxychloroquine and broad-spectrum antibiotics (piperacillin-tazobactam plus teicoplanin). No GI symptoms were reported during hospitalisation, but a lung contrast-enhancement CT (CE-CT) excluding thromboembolism showed, as collateral finding, intraperitoneal free bubbles not present on a previous CT examination; the subsequent abdominal CE-CT described pneumatosis intestinalis (PI) involving the caecum and the right colon. Ciprofloxacin plus metronidazole was started, and the 2-week follow-up CT showed the complete resolution of PI. DISCUSSION: The pathogenesis of PI is poorly understood. PI involving the caecum and right colon has been described for HIV and Cytomegalovirus infections, but, to our best knowledge, never before in COVID-19. We hypothesise a multifactorial aetiopathogenesis for PI, with a possible role of the bowel wall damage and microbiota impairment due to SARS-CoV-2 infection, and we suggest a conservative management in the absence of symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.