ArticleParasites & vectors2020
Serological evaluation of selected vector-borne pathogens in owned dogs from northern Spain based on a multicenter study using a commercial test.
Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Canine Leishmaniasis in Europe over the Last Decade: A Review of Geographic Trends and Epidemiological Data.Pathogens (Basel, Switzerland) · 2025Pooled it
- Serological and molecular positivity for Leishmania infantum in dogs referred to two veterinary hospitals in Barcelona, Spain.Parasites & vectors · 2026Article
- Nationwide seroprevalence of canine vector-borne pathogens in dogs in Spain.Parasites & vectors · 2026Article
- Large-scale randomized double-blind field clinical trial for safety and efficacy assessment of the DNA vaccine Neoleish against canine leishmaniasis.PLoS neglected tropical diseases · 2025Article
- Seroprevalence, clinical investigation, and risk factors associated withJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- Serological detection of Anaplasma spp., Ehrlichia spp., Borrelia burgdorferi s.l. antibodies, and Dirofilaria immitis antigen in stray dogs in Bosnia and Herzegovina.Parasitology research · 2025Article
- High seroprevalence of selected vector-borne pathogens in dogs from Saipan, Northern Mariana Islands.Parasites & vectors · 2025Article
- Twenty-year evolution of Leishmania infantum infection in dogs in Valdeorras (Galicia, Northwestern Spain): implication of climatic factors and preventive measures.Parasites & vectors · 2024Article
- Genetic Variability in Leishmaniasis-CausingAnimals : an open access journal from MDPI · 2024Article
- Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease.Pathogens (Basel, Switzerland) · 2024Review
- Haematochemical Profile of Healthy Dogs Seropositive for Single or Multiple Vector-Borne Pathogens.Veterinary sciences · 2024Article
- Prevalence of asymptomatic Leishmania infection and knowledge, perceptions, and practices in blood donors in mainland Portugal.Parasites & vectors · 2023Article
- A blinded, randomized and controlled multicenter clinical trial to assess the efficacy and safety of LeisguardParasites & vectors · 2023Article
- Serological survey of Leishmania infantum in apparently healthy dogs in different areas of Spain.Veterinary medicine and science · 2023Article
- The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005-2020.PLoS neglected tropical diseases · 2023Review
- Seroprevalence and Risk Factors Associated withMicroorganisms · 2022Article
- What Has Happened to Heartworm Disease in Europe in the Last 10 Years?Pathogens (Basel, Switzerland) · 2022Review
- Distribution of Tick-Borne Pathogens in Domestic Animals and Their Ticks in the Countries of the Mediterranean Basin between 2000 and 2021: A Systematic Review.Microorganisms · 2022Article
- Seropositivity of main vector-borne pathogens in dogs across Europe.Parasites & vectors · 2022Article
- Expansion of Canine Heartworm in Spain.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnvironmental conditions in northern Spain allow the development of different arthropods involved in the transmission of significant canine vector-borne pathogens. The aim of the study was to systematically assess seroprevalence rates for Leishmania infantum, Ehrlichia canis, Anaplasma spp., Dirofilaria immitis and Borrelia burgdorferi, and risk factors in dogs from all regions of the north of Spain.
methodsA total of 556 dogs were included in this study between January 2017 and December 2018, belonging to 30 practices covering all regions in northern Spain (Galicia, Asturias, Cantabria, Basque Country, Navarra, Aragon and Catalonia). All practices were located in the north of every region. Blood samples were analyzed using the 4DX SNAP® test (IDEXX Laboratories, Westbrook, Maine, USA) for the detection of D. immitis antigen and E. canis, B. burgdorferi and Anaplasma spp. antibodies. Leishmania SNAP® test (IDEXX Laboratories) was used for detection of L. infantum antibodies. Associations between prevalence of canine vector-borne pathogens, epidemiological and clinical signs data were statistically analyzed.
resultsThe overall prevalence rates were 8.99% for L. infantum, 1.26% for Anaplasma spp., 0.9% for E. canis, 0.72% for B. burgdorferi, and 0.18% for D. immitis. Globally, 11.33% of the dogs included in the study were positive to any tested vector-borne pathogen. Leishmania infantum seroprevalence was the highest and the only one detected in all the regions. Leishmania infantum seropositivity was associated with age > 10 years-old, outdoor access, anemia, fever, dermatological signs, lympadenomegaly, muscular atrophy, ocular signs and renal disease. Ehrlichia canis seropositivity was associated with the summer season and living in urban areas. Apathy, weakness, anorexia, weight loss, anemia, fever and gastrointestinal clinical signs were also associated with E. canis antibody detection. Living in a rural area was also a risk factor for Anaplasma spp. and B. burgdorferi seropositivity.
conclusionsTo our knowledge, this is the first multicenter survey performed in northern Spain assessing different canine vector-borne diseases from all regions. Results show the presence of autochthonous cases of these diseases. The vector-borne pathogens found in this study should be included in the differential diagnosis in dogs from some areas previously considered non-endemic for these pathogens.
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