Evidence map›Paper›PMID 32522223›Full record

ArticleJournal of experimental & clinical cancer research : CR2020

A moonshot approach toward the management of cancer patients in the COVID-19 time: what have we learned and what could the Italian network of cancer centers (Alliance Against Cancer, ACC) do after the pandemic wave?

Nicola Silvestris, Giovanni Apolone, Gerardo Botti, Gennaro Ciliberto, Massimo Costantini, Paolo De Paoli, Silvia Franceschi, Giuseppe Opocher, Angelo Paradiso, Paolo Pronzato and 2 more

Abstract readLetter
In one paragraph

Article in Journal of experimental & clinical cancer research : CR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicola SilvestrisIRCCS Istituto Tumori "Giovanni Paolo II", 70124, Bari, Italy. n.silvestris@oncologico.bari.it.ORCID http://orcid.org/0000-0001-7814-7318
Giovanni ApoloneScientific Directorate, Fondazione IRCCS Istituto Tumori di Milano, Milan, Italy.
Gerardo BottiScientific Directorate, Istituto Nazionale Tumori, "Fondazione G. Pascale" - IRCCS Naples, Naples, Italy.
Gennaro CilibertoScientific Directorate, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Massimo CostantiniScientific Directorate, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Paolo De PaoliAlliance Against Cancer, Rome, Italy.
Silvia FranceschiScientific Directorate, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Giuseppe OpocherScientific Directorate, Veneto Institute of Oncology, IOV-IRCCS, Padova, Italy.
Angelo ParadisoScientific Directorate IRCCS Istituto Tumori "Giovanni Paolo II" of Bari, Bari, Italy.
Paolo PronzatoDepartment of Oncology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Alessandro SgambatoScientific Directorate IRCCS CROB Rionero in Vulture, Rionero in Vulture, Italy.
Ruggero De MariaAlliance Against Cancer, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

If we focus our attention on seven main features of COVID-19 infection (heterogeneity, fragility, lack of effective treatments and vaccines, "miraculous cures", psychological suffering, deprivation, and globalization), we may establish parallelism with the challenges faced in the steep road to the understanding and treatment of neoplastic diseases. How the similarities between these two conditions can help us cope with the emergency effort represented by the management of cancer patients in the COVID-19 era, today and in the future? In a manner similar to the Cancer Moonshot initiative in the United States, we can hypothesize a multinational moonshot project towards the management of cancer patients during COVID-19 pandemic. In particular, we believe that the main road to elaborate meaningful scientific evidence is represented by the collection of all the data on COVID-19 and cancer comorbidity that are and will become available in cancer centers, coupled with the design of large clinical studies. To address this goal, it is essential to identify the entity that can produce this scientific evidences and the potentially most successful research strategy to undertake. The largest Italian organization for cancer research, Alliance Against Cancer (Alleanza Contro il Cancro, ACC), is called to play a scientific leadership in addressing these challenges, which requires the coordination of oncology teams at regional, national, and international levels. To fulfill this commitment, ACC will create a liaison with health government agencies in order to develop "dynamic" indications able to fight such an unpredictable pandemic.

Indexed as

PandemicsBetacoronavirusCoronavirus InfectionsCOVID-19Government AgenciesHumansItalyMedical OncologyNeoplasmsPneumonia, ViralSARS-CoV-2Alliance against CancerCancerCOVID-19ResearchTherapy

Identifiers

PMID32522223
PMCPMC7286743

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.