Evidence map›Paper›PMID 32522192›Full record

ArticleLipids in health and disease2020

Gaps in beliefs and practice in dyslipidaemia management in Japan, Germany, Colombia and the Philippines: insights from a web-based physician survey.

Philip J Barter, Shizuya Yamashita, Ulrich Laufs, Alvaro J Ruiz, Rody Sy, Mark David G Fang, Emanuela Folco, Peter Libby, Yuji Matsuzawa, Raul D Santos

Open access · goldFull text read
In one paragraph

Article in Lipids in health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  9. Changes in Our Times and in Cholesterol Targets.Arquivos brasileiros de cardiologia · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 9 countries.

Philip J BarterSchool of Medical Sciences, University of New South Wales, Sydney, Australia.
Shizuya YamashitaRinku General Medical Center and Osaka University Graduate School of Medicine, Osaka, Japan.
Ulrich LaufsUniversitatsklinikum Leipzig, Leipzig, Germany.
Alvaro J RuizPontificia Universidad Javeriana, Bogota, Colombia.
Rody SyCollege of Medicine, University of the Philippines-Manila, Manila, the Philippines.
Mark David G FangCardinal Santos Medical Center, San Juan City, MetroManila, the Philippines.
Emanuela FolcoInternational Atherosclerosis Society, Viale Piave 35, Milan, Italy.
Peter LibbyBrigham and Women's Hospital, Harvard Medical School, Boston, USA.
Yuji MatsuzawaSumitomo Hospital, Osaka, Japan.
Raul D SantosHospital Israelita Albert Einstein, São Paulo, Brazil. rauldsf@gmail.com.ORCID http://orcid.org/0000-0002-9860-6582
Brigham and Women's Hospital · USEuropean Society of Hypertension · ITPontificia Universidad Javeriana · COSumitomo Hospital · JPThe University of Osaka · JPUniversidade de São Paulo · BRUniversity Hospital Leipzig · DEUniversity of the Philippines Manila · PHUNSW Sydney · AU

Funding

Amgen None
6 · The paper itself

Abstract

backgroundImplementing evidence-based management of dyslipidaemia is a challenge worldwide.

objectivesTo understand physician beliefs and behaviour and identify uncertainties in dyslipidaemia management across four world regions.

methodsWeb-based survey of 1758 physicians in Japan, Germany, Colombia and the Philippines who were selected randomly from existing databases. Key inclusion criteria were 1) for cardiologists and diabetes/endocrinology specialists: ≥50 dyslipidaemia patients examined in the last month; 2) for specialists in neurology/neurosurgery/stroke medicine: ≥50 dyslipidaemia patients and ≥ 20 patients with a history of ischaemic stroke examined in the last month; and 3) for specialists in nephrology and general medicine: based at centres with ≥20 beds and ≥ 50 dyslipidaemia patients examined in the last month. The self-report survey covered dyslipidaemia management, target low-density lipoprotein cholesterol (LDL-C) levels in different patient groups, and statin safety. All physicians gave voluntary consent and all data were anonymised. Analysis was solely descriptive.

resultsThe survey highlighted key areas of uncertainty in dyslipidaemia management in the four countries. These related to LDL-C targets in different patient groups, the safety of low LDL-C levels, the safety of statins, especially for effects on cognitive, renal and hepatic function and for haemorrhagic stroke risk, and lipid management strategies in patients with chronic kidney disease, including those with concomitant hypertriglyceridaemia.

conclusionsThis survey of physicians in Japan, Germany, Colombia and the Philippines has identified key gaps in knowledge about dyslipidaemia management. These relate to the safety of low LDL-C levels, the safety of statins, and lipid management of chronic kidney disease. The findings from this survey highlight the need for further education to improve the implementation of guideline recommendations for dyslipidaemia management.

Indexed as

InternetSurveys and QuestionnairesAttitude of Health PersonnelCardiovascular DiseasesCholesterol, LDLColombiaDyslipidemiasGermanyHumansHydroxymethylglutaryl-CoA Reductase InhibitorsJapanPhilippinesPhysiciansPractice Patterns, Physicians'Renal Insufficiency, ChronicCholesterol, LDLHydroxymethylglutaryl-CoA Reductase InhibitorsAtherosclerotic cardiovascular diseaseChronic kidney diseaseHaemorrhagic strokeLow-density lipoprotein cholesterolSafetyStatins

Identifiers

PMID32522192
PMCPMC7285462
OpenAlexW3033572859

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.