Evidence map›Paper›PMID 32522058›Full record

ReviewJournal of psychopharmacology (Oxford, England)2020

Medical cannabis in the UK: From principle to practice.

Anne Katrin Schlag, David S Baldwin, Michael Barnes, Steve Bazire, Rachel Coathup, H Valerie Curran, Rupert McShane, Lawrence D Phillips, Ilina Singh, David J Nutt

Abstract readReview
In one paragraph

Review in Journal of psychopharmacology (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Cannabis use by individuals with spinal cord injury in the UK: a call for improved patient education and physician awareness for pain and spasticity management.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Observational
  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anne Katrin SchlagDrug Science, London, UK.ORCID 0000-0003-2074-1917
David S BaldwinClinical and Experimental Sciences, University of Southampton, Southampton, UK.
Michael BarnesUniversity of Newcastle, Newcastle upon Tyne, UK.
Steve BazireSchool of Pharmacy, University of East Anglia, Norwich, UK.
Rachel CoathupUniversity of Manchester, Manchester, UK.
H Valerie CurranClinical, Education and Health Psychology, University College London, London, UK.
Rupert McShaneInterventional Psychiatry Service, Oxford Health NHS Foundation Trust, Oxford, UK.
Lawrence D PhillipsDepartment of Management, London School of Economics & Political Science, London, UK.
Ilina SinghDepartment of Psychiatry, University of Oxford, Oxford, UK.
David J NuttDepartment of Brain Sciences, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the UK, medical cannabis was approved in November 2018, leading many patients to believe that the medicine would now be available on the NHS. Yet, to date, there have been only 12 NHS prescriptions and less than 60 prescriptions in total. In marked contrast, a recent patient survey by the Centre for Medical Cannabis (Couch, 2020) found 1.4 m people are using illicit cannabis for medical problems.

aimsSuch a mismatch between demand and supply is rare in medicine. This article outlines some of the current controversies about medical cannabis that underpin this disparity, beginning by contrasting current medical evidence from research studies with patient-reported outcomes. OUTCOMES: Although definite scientific evidence is scarce for most conditions, there is significant patient demand for access to medical cannabis. This disparity poses a challenge for prescribers, and there are many concerns of physicians when deciding if, and how, to prescribe medical cannabis which still need to be addressed. Potential solutions are outlined as to how the medical profession and regulators could respond to the strong demand from patients and families for access to medical cannabis to treat chronic illnesses when there is often a limited scientific evidence base on whether and how to use it in many of these conditions.

conclusionsThere is a need to maximise both clinical research and patient benefit, in a safe, cautious and ethical manner, so that those patients for whom cannabis is shown to be effective can access it. We hope our discussion and outlines for future progress offer a contribution to this process.

Indexed as

CannabinoidsDrug PrescriptionsMedical MarijuanaPractice Guidelines as TopicHumansUnited KingdomCannabinoidsMedical MarijuanacannabidiolCannabisd9 Tetrahydrocannabinol (d9THC)medical cannabispatient access

Identifiers

PMID32522058
PMCPMC7436434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.