ArticleJournal of clinical medicine2020
Nonimmune Hydrops Fetalis-Prenatal Diagnosis, Genetic Investigation, Outcomes and Literature Review.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 26 citations in OpenAlex.
- Non-immune hydrops fetalis (NIHF): diagnostic evaluation and lessons learned from a case series.Future science OA · 2026Article
- Premature Ductus Arteriosus Constriction and Pulmonary Trunk Dilation in a Case of Non-Immune Hydrops Fetalis With Trisomy 21.Clinical case reports · 2026Article
- Extracorporeal membrane oxygenation in Non-Immune Hydrops fetalis - a registry-based data analysis over the last 25 years.European journal of pediatrics · 2026Observational
- Fetal Hydrops: Genetic Dissection of an Unspecific Sonographic Finding-A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2025Review
- Recurrent Non-Immune Hydrops Fetalis: A Diagnostic Dilemma-"What to tell the Prospective Parents".Journal of obstetrics and gynaecology of India · 2022Article
- Etiology and outcome of non-immune hydrops fetalis in relation to gestational age at diagnosis and intrauterine treatment.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Mirror syndrome with noncompaction cardiomyopathy in the mother and fetus. Case reportRevista colombiana de obstetricia y ginecologia · 2021Article
- Nonimmune hydrops fetalis diagnosed at 35 weeks gestation - a case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this paper is to review the outcomes and discuss the genetic and non-genetic aetiology of nonimmune hydrops fetalis in order to support differential ultrasound and genetic evaluations and family counselling. This single-centre study includes all cases of nonimmune hydrops fetalis diagnosed prenatally from 2009 to 2019. Two sources of data were used for this study (prenatal and neonatal) to compare and summarise the findings. Data from genetic testing and ultrasound scans were collected. In total, 33 pregnant women with prenatally diagnosed nonimmune hydrops fetalis were studied. The data included 30 cases of singleton (91%) and three cases (9%) of twin pregnancies. There were 14 survivors (43%), seven cases of postnatal deaths (21%), four cases of intrauterine foetal demises (12%), four cases of termination of pregnancy (12%), and four women without a follow up (12%). The total number of chromosomally normal singleton pregnancies was 29 (88%), and 14 foetuses had an anatomical abnormality detected on the ultrasound scan. The chance of survival was the highest in cases of isolated, idiopathic hydrops fetalis, which in most cases was due to an undetectable intrauterine infection. In many cases, the diagnosis could not be established throughout pregnancy. Each case of nonimmune hydrops fetalis should thus be analysed individually.
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