Evidence map›Paper›PMID 32521786›Full record

ArticleJournal of clinical medicine2020

Trends and Between-Physician Variation in Laboratory Testing: A Retrospective Longitudinal Study in General Practice.

Lisa D Schumacher, Levy Jäger, Rahel Meier, Yael Rachamin, Oliver Senn, Thomas Rosemann, Stefan Markun

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lisa D SchumacherInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.
Levy JägerInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.
Rahel MeierInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-8159-9753
Yael RachaminInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.
Oliver SennInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.
Thomas RosemannInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-6436-6306
Stefan MarkunInstitute of Primary Care, University and University Hospital Zurich, 8091 Zurich, Switzerland.
University Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratory tests are frequently ordered by general practitioners (GPs), but little is known about time trends and between-GP variation of their use. In this retrospective longitudinal study, we analyzed over six million consultations by Swiss GPs during the decade 2009-2018. For 15 commonly used test types, we defined specific laboratory testing rates (sLTR) as the percentage of consultations involving corresponding laboratory testing requests. Patient age- and sex-adjusted time trends of sLTR were modeled with mixed-effect logistic regression accounting for clustering of patients within GPs. We quantified between-GP variation by means of intraclass correlation coefficients (ICC). Nine out of the 15 laboratory test types considered showed significant temporal increases, most eminently vitamin D (ten-year odds ratio (OR) 1.88, 95% confidence interval (CI) 1.71-2.06) and glycated hemoglobin (ten-year OR 1.87, 95% CI 1.82-1.92). Test types both subject to substantial increase and high between-GP variation of sLTR were vitamin D (ICC 0.075), glycated hemoglobin (ICC 0.101), C-reactive protein (ICC 0.202), and vitamin B12 (ICC 0.166). Increasing testing frequencies and large between-GP variation of specific test type use pointed at inconsistencies of medical practice and potential overuse.

Indexed as

general practiceintraclass correlation coefficientlaboratory testingmixed-effect modeltrend

Identifiers

PMID32521786
PMCPMC7355885
OpenAlexW3033471718

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.