Evidence map›Paper›PMID 32521736›Full record

Trial reportBiomolecules2020

The Effect of Escitalopram on Central Serotonergic and Dopaminergic Systems in Patients with Cervical Dystonia, and Its Relationship with Clinical Treatment Effects: A Double-Blind Placebo-Controlled Trial.

Evelien Zoons, Marina A J Tijssen, Yasmine E M Dreissen, Marenka Smit, Jan Booij

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Cognitive and Neuropsychiatric Impairment in Dystonia.Current neurology and neuroscience reports · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Evelien ZoonsDepartment of Neurology, Zaans Medisch Centrum, 1502 DV Zaandam, The Netherlands.
Marina A J TijssenDepartment of Neurology, University Medical Centre, 9713 GZ Groningen, The Netherlands.
Yasmine E M DreissenDepartment of Neurosurgery, Amsterdam University Medical Centre, location Academic Medical Centre, 1100 DD Amsterdam, The Netherlands.
Marenka SmitDepartment of Neurology, University Medical Centre, 9713 GZ Groningen, The Netherlands.
Jan BooijDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location Academic Medical Centre, 1100 DD Amsterdam, The Netherlands.
University Medical Center Groningen · NLAmsterdam UMC Location University of Amsterdam · NLZaans Medisch Centrum · NL

Funding

AMC Graduate School n/AONWAR imaging fund N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CitalopramCross-Over StudiesDopamine Plasma Membrane Transport ProteinsDouble-Blind MethodFemaleHumansMaleMiddle AgedReceptors, Dopamine D2Receptors, Dopamine D3Selective Serotonin Reuptake InhibitorsSerotonin Plasma Membrane Transport ProteinsTorticollisCitalopramDopamine Plasma Membrane Transport ProteinsReceptors, Dopamine D2Receptors, Dopamine D3Selective Serotonin Reuptake InhibitorsSerotonin Plasma Membrane Transport ProteinsSLC6A3 protein, humanSLC6A4 protein, humancervical dystoniadopamine serotoninescitalopramsingle-photon emission computed tomography (SPECT)

Identifiers

PMID32521736
PMCPMC7355711
OpenAlexW3033736560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.