Evidence map›Paper›PMID 32521698›Full record

ArticleInternational journal of molecular sciences2020

Chrysosplenol d, a Flavonol from

Sophia J Lang, Michael Schmiech, Susanne Hafner, Christian Paetz, Katharina Werner, Menna El Gaafary, Christoph Q Schmidt, Tatiana Syrovets, Thomas Simmet

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Unveiling the multifaceted potential ofJournal of pharmaceutical analysis · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Journal of experimental pharmacology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. American journal of cancer research · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Constituents ofMolecules (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sophia J LangInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.
Michael SchmiechInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0003-4350-0331
Susanne HafnerInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0003-0663-8382
Christian PaetzResearch Group Biosynthesis/Nuclear Magnetic Resonance, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany.ORCID 0000-0002-5776-7574
Katharina WernerInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.
Menna El GaafaryInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.
Christoph Q SchmidtInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.
Tatiana SyrovetsInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-6751-2233
Thomas SimmetInstitute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany.
Universität Ulm · DECairo University · EGMax Planck Institute for Chemical Ecology · DE

Funding

State Ministry for Sciences, Research and Arts, Baden-Württemberg AZKIM
6 · The paper itself

Abstract

Triple negative human breast cancer (TNBC) is an aggressive cancer subtype with poor prognosis. Besides the better-known artemisinin,

Indexed as

AnimalsAntineoplastic Agents, PhytogenicApoptosisArtemisia annuaCell Line, TumorCell Membrane PermeabilityCell SurvivalDisease Models, AnimalFemaleFlavonesFlavonoidsFlavonolsHumansMAP Kinase Signaling SystemMiceMitochondriaAntineoplastic Agents, Phytogeniccasticinchrysosplenol DFlavonesFlavonoidsFlavonolsapoptosisartemisia annuacasticincell cyclechick chorioallantoic membrane assaychrysosplenol dmethoxylated flavonoidsmitogen-activated protein kinasetriple negative breast cancer

Identifiers

PMID32521698
PMCPMC7312517
OpenAlexW3033303957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.