Evidence map›Paper›PMID 32521643›Full record

ArticleJournal of clinical medicine2020

COVID-19 and Congenital Heart Disease: Results from a Nationwide Survey.

Jolanda Sabatino, Paolo Ferrero, Massimo Chessa, Francesco Bianco, Paolo Ciliberti, Aurelio Secinaro, Lilia Oreto, Martina Avesani, Valentina Bucciarelli, Giuseppe Calcaterra and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Impacts of COVID-19 on pediatric patients with congenital heart disease: a small systematic and integrative literature review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
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  13. Arrhythmia and COVID-19 in children.Clinical and experimental pediatrics · 2023
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  16. COVID-19 in Cyanotic Congenital Heart Disease.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
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  17. COVID-19 in congenital heart disease patients: what did we learn?!Frontiers in cardiovascular medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 2 countries.

Jolanda SabatinoDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.ORCID 0000-0002-1661-5419
Paolo FerreroPediatric cardiology and ACHD, Cardiovascular Department, ASST Papa Giovanni 23, 24127 Bergamo, Italy.
Massimo ChessaACHD UNIT-Pediatric and Adult Congenital Heart Centre, IRCCS-Policlinico San Donato, 20097 Milan, Italy.
Francesco BiancoPediatric and Congenital Cardiology Unit, Azienda Ospedaliero Universitaria Ancona, 60126 Ancona, Italy.ORCID 0000-0001-9785-3402
Paolo CilibertiPediatric Cardiology and Cardiac Surgery Department, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Aurelio SecinaroDepartment of Imaging, Advanced Cardiovascular Imaging Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Lilia OretoMediterranean Pediatric Cardiology Center, Bambino Gesù Pediatric Hospital, 98039 Taormina (ME), Italy.
Martina AvesaniDepartment of Women's and Children's Health, University of Padua, 35122 Padua, Italy.
Valentina BucciarelliPediatric and Congenital Cardiology Unit, Azienda Ospedaliero Universitaria Ancona, 60126 Ancona, Italy.
Giuseppe CalcaterraDepartment of Cardiology, University of Palermo, 90133 Palermo, Italy.
Maria Pia CalabròDepartment of Human Pathology of Adulthood and Childhood, University of Messina, 98125 Messina, Italy.
Maria Giovanna RussoDepartment of Cardiology, Luigi Vanvitelli University of Naples, Monaldi Hospital, 80131 Naples, Italy.
Pier Paolo BassareoUniversity College of Dublin, Mater Misericordiae University Hospital, Dublin 4, Ireland.
Paolo GuccionePediatric Cardiology and Cardiac Surgery Department, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Ciro IndolfiDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.ORCID 0000-0003-1241-6487
Giovanni Di SalvoDepartment of Women's and Children's Health, University of Padua, 35122 Padua, Italy.
Bambino Gesù Children's Hospital · ITMagna Graecia University · ITOspedali Riuniti di Ancona · ITUniversity of Padua · ITIRCCS Policlinico San Donato · ITMater Misericordiae University Hospital · IEOspedale Papa Giovanni XXIII · ITUniversity of Messina · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pandemic of Novel Coronavirus Disease 2019 (COVID-19) is challenging, given the large number of hospitalized patients. Cardiovascular co-morbidities are linked to a higher mortality risk. Thus, patients with Congenital Heart Disease (CHD) might represent a high-risk population. Nevertheless, no data about them are available, yet. Hence, we conducted a nationwide survey to assess clinical characteristics and outcomes in patients with congenital heart disease affected by COVID-19. METHODS AND

resultsThis is a multi-centre, observational, nationwide survey, involving high-volume Italian CHD centres. COVID-19 diagnosis was defined as either "clinically suspected" or "confirmed", where a severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) test had been performed and was positive. Cardiovascular comorbidities were observed among adult patients-atrial fibrillation (seven; 9%), hypertension (five; 7%), obesity (seven; 9%) and diabetes (one; 1%)-but were absent among children. Cardiovascular complications were mainly observed in the "confirmed" COVID-19

conclusionsDespite previous reports pointing to a higher case-fatality rate among patients with cardiovascular co-morbidities, we observed a mild COVID-19 clinical course in our cohort of CHD patients. Although these results should be confirmed in larger cohorts to investigate the underlying mechanisms, the findings of low cardiovascular complications rates and no deaths are reassuring for CHD patients.

Indexed as

cardiovascular complicationscongenital heart diseaseCOVID-19

Identifiers

PMID32521643
PMCPMC7355526
OpenAlexW3033804942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.