Evidence map›Paper›PMID 32521627›Full record

ReviewPharmaceutics2020

Functional Nanofibrous Biomaterials of Tailored Structures for Drug Delivery-A Critical Review.

Zhen Li, Shunqi Mei, Yajie Dong, Fenghua She, Yongzhen Li, Puwang Li, Lingxue Kong

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Living Nanofiber-Enabled Cardiac Patches for Myocardial Injury.JACC. Basic to translational science · 2025
    Review
  3. Review
  4. Biomaterials for Drug Delivery and Human Applications.Materials (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Static and Dynamic Biomaterial Engineering for Cell Modulation.Nanomaterials (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Multi-Functional Core-Shell Nanofibers for Wound Healing.Nanomaterials (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhen LiInstitute for Frontier Materials, Deakin University, Geelong, Victoria 3216, Australia.ORCID 0000-0002-7689-0439
Shunqi MeiSchool of Mechanical Engineering and Automation, Wuhan Textile University, Wuhan 430073, China.
Yajie DongInstitute for Frontier Materials, Deakin University, Geelong, Victoria 3216, Australia.
Fenghua SheInstitute for Frontier Materials, Deakin University, Geelong, Victoria 3216, Australia.
Yongzhen LiKey laboratory of Tropical Crop Products Processing, Ministry of Agriculture and Rural Affairs, Agriculture Products Processing Research Institute, CATAS, Zhanjiang 524001, China.
Puwang LiKey laboratory of Tropical Crop Products Processing, Ministry of Agriculture and Rural Affairs, Agriculture Products Processing Research Institute, CATAS, Zhanjiang 524001, China.
Lingxue KongInstitute for Frontier Materials, Deakin University, Geelong, Victoria 3216, Australia.ORCID 0000-0001-6219-3897

Funding

Central Public-interest Scientific Institution Basal Research Fund for Innovative Research Team Program of CATAS 1630122017009National Natural Science Foundation of China 51175385Science and Technology Program of Hubei Province 2018AAA036
6 · The paper itself

Abstract

Nanofibrous biomaterials have huge potential for drug delivery, due to their structural features and functions that are similar to the native extracellular matrix (ECM). A wide range of natural and polymeric materials can be employed to produce nanofibrous biomaterials. This review introduces the major natural and synthetic biomaterials for production of nanofibers that are biocompatible and biodegradable. Different technologies and their corresponding advantages and disadvantages for manufacturing nanofibrous biomaterials for drug delivery were also reported. The morphologies and structures of nanofibers can be tailor-designed and processed by carefully selecting suitable biomaterials and fabrication methods, while the functionality of nanofibrous biomaterials can be improved by modifying the surface. The loading and releasing of drug molecules, which play a significant role in the effectiveness of drug delivery, are also surveyed. This review provides insight into the fabrication of functional polymeric nanofibers for drug delivery.

Indexed as

biopolymersdrug deliverynanofiber technologynanofibrous biomaterialsnature fiber biomaterials

Identifiers

PMID32521627
PMCPMC7355603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.