Evidence map›Paper›PMID 32521616›Full record

ArticleMicroorganisms2020

Switching to Integrase Inhibitors Unlinked to Weight Increase in Perinatally HIV-Infected Young Adults and Adolescents: A 10-Year Observational Study.

Lucia Taramasso, Antonio Di Biagio, Francesca Bovis, Federica Forlanini, Elena Albani, Rebecka Papaioannu, Vania Giacomet

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lucia TaramassoInfectious Diseases Unit, Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy.
Antonio Di BiagioInfectious Diseases Clinic, Department of Health Sciences (DiSSal), University of Genoa, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0003-1436-5089
Francesca BovisBiostatistics Unit, Department of Health Sciences (DiSSal), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-3823-4000
Federica ForlaniniPediatric Infectious Disease Unit, ASST Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.ORCID 0000-0001-7812-6322
Elena AlbaniPediatric Infectious Disease Unit, ASST Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.
Rebecka PapaioannuInfectious Diseases Clinic, Department of Health Sciences (DiSSal), University of Genoa, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Vania GiacometPediatric Infectious Disease Unit, ASST Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.
University of Milan · ITOspedale Policlinico San Martino · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An unexpected increase in weight gain has recently been reported in the course of integrase strand transfer inhibitors (INSTI) treatment. The possibility of this effect in people who are perinatally infected with HIV (PHIV) and thus exposed to lifelong therapy needs to be explored. This is a retrospective multicenter case-control study. Adults with PHIV followed between 2010 and 2019 in two outpatient services in Northern Italy were included if they had at least two weight measures in two successive years of observation. Patients were considered as cases if they were switched to INSTI (INSTI group), or controls if they were never exposed to INSTI (non-INSTI group). The date of the switch in cases was considered to be the baseline (T

Indexed as

HIV metabolic complicationintegrase strand transfer inhibitorperinatal HIV infectionweight gain

Identifiers

PMID32521616
PMCPMC7356820
OpenAlexW3034017346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.