Evidence map›Paper›PMID 32521598›Full record

ReviewChildren (Basel, Switzerland)2020

Allergen Immunotherapy in Pediatric Asthma: A Pragmatic Point of View.

Michele Miraglia Del Giudice, Amelia Licari, Ilaria Brambilla, Maria Angela Tosca, Giorgio Ciprandi

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Pediatric Asthma: A Daily Challenge.Children (Basel, Switzerland) · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80100 Naples, Italy.
Amelia LicariDepartment of Pediatrics, Pediatrics Clinic, Ospedale San Matteo, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-1773-6482
Ilaria BrambillaDepartment of Pediatrics, Pediatrics Clinic, Ospedale San Matteo, University of Pavia, 27100 Pavia, Italy.
Maria Angela ToscaDepartment of Pediatrics, Allergy Center, Istituto G. Gaslini, 16100 Genoa, Italy.
Giorgio CiprandiAllergy Clinic, Casa di Cura Villa Montallegro, 16100 Genoa, Italy.ORCID 0000-0001-7016-8421

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, the only disease-modifying treatment strategy for allergic rhinitis and asthma is allergen immunotherapy (AIT). There is evidence that AIT improves allergic rhinitis and asthma, such as reducing symptom severity and medication use and improving of quality of life, with a long-lasting effect after the end of the course. The recent clinical trials evidenced AIT effectiveness and safety in allergic asthma. Consequently, the current version of the GINA (Global Initiative for Asthma) guidelines recommend AIT as an add-on therapy for asthma. There is also evidence that AIT may exert preventive activity on the possible progression from allergic rhinitis to asthma in children and the onset of new sensitizations. The present review provides a pragmatic summary of the clinical indications of AIT in pediatric asthma, including the immunological mechanisms, the predictive biomarkers, and the safety issues in clinical practice.

Indexed as

allergen-specific immunotherapyallergic asthmachildrensubcutaneous immunotherapysublingual immunotherapy

Identifiers

PMID32521598
PMCPMC7346201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.