Evidence map›Paper›PMID 32521476›Full record

ArticleNeuroImage. Clinical2020

Mapping typical and hypokinetic dysarthric speech production network using a connected speech paradigm in functional MRI.

Shalini Narayana, Megan B Parsons, Wei Zhang, Crystal Franklin, Katherine Schiller, Asim F Choudhri, Peter T Fox, Mark S LeDoux, Michael Cannito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Shalini NarayanaDepartment of Pediatrics, Division of Pediatric Neurology, University of Tennessee Health Science Center, Memphis, TN 38103, USA; Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA; Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38103, USA. Electronic address: snaraya2@uthsc.edu.
Megan B ParsonsSchool of Communication Sciences and Disorders, University of Memphis, Memphis, TN 38152, USA.
Wei ZhangResearch Imaging Institute, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
Crystal FranklinResearch Imaging Institute, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
Katherine SchillerDepartment of Pediatrics, Division of Pediatric Neurology, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Asim F ChoudhriNeuroscience Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA; Department of Radiology, Division of Neuroradiology, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Peter T FoxResearch Imaging Institute, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
Mark S LeDouxVeracity Neuroscience LLC, Memphis, TN 38157, USA; Department of Psychology and School of Health Studies, University of Memphis, Memphis, TN 38152, USA.
Michael CannitoDepartment of Communicative Disorders, University of Louisiana at Lafayette, USA.
The University of Texas Health Science Center at San Antonio · USUniversity of Memphis · USUniversity of Tennessee Health Science Center · USLe Bonheur Children's Hospital · USUniversity of Louisiana at Lafayette · US

Funding

Expanding a Neural Model of Speech Using Virtual Lesions and Connectivity StudiesR21DC009467 · NIDCD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI NARAYANA, SHALINI · 2009 to 2010
$406k
IMAGING AND MODELING THERAPEUTIC MECHANISMS OF ACTIONR21NS043738 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI FOX, PETER THORNTON · 2002 to 2003
$351k
NIDCD NIH HHS R21 DC009467NINDS NIH HHS R21 NS043738
6 · The paper itself

Abstract

We developed a task paradigm whereby subjects spoke aloud while minimizing head motion during functional MRI (fMRI) in order to better understand the neural circuitry involved in motor speech disorders due to dysfunction of the central nervous system. To validate our overt continuous speech paradigm, we mapped the speech production network (SPN) in typical speakers (n = 19, 10 females) and speakers with hypokinetic dysarthria as a manifestation of Parkinson disease (HKD; n = 21, 8 females) in fMRI. We then compared it with the SPN derived during overt speech production by

Indexed as

AdultBrainBrain MappingComprehensionDysarthriaFemaleHumansMagnetic Resonance ImagingMaleSpeechSpeech DisordersVoice DisordersYoung AdultConnected speechfMRIHypokinetic dysarthriaMotor speech disordersNormal speechPETSpeech productionSpeech production network

Identifiers

PMID32521476
PMCPMC7284131
OpenAlexW3033342131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.