Evidence map›Paper›PMID 32521390›Full record

SynthesisClinical psychology review2020

Moving towards specificity: A systematic review of cue features associated with reward and punishment in anorexia nervosa.

Ann F Haynos, Jason M Lavender, Jillian Nelson, Scott J Crow, Carol B Peterson

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical psychology review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Article
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  8. Review
  9. Avoidance habit learning in adolescents and young women with anorexia nervosa: an fMRI study.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  10. Review
  11. Investigating Associations Between General and Disorder-Specific Reward and Suicidality in Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  12. Article
  13. Does Evidence Support an Emotion Regulation Model of Anorexia Nervosa? A Systematic Review of Over a Decade of Research.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025
    Article
  14. Food choice and neural reward systems in adolescents with anorexia nervosa and atypical anorexia nervosa.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ann F HaynosDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States of America. Electronic address: afhaynos@umn.edu.
Jason M LavenderMilitary Cardiovascular Outcomes Research (MiCOR) Program, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, United States of America; The Metis Foundation, San Antonio, TX, United States of America.
Jillian NelsonDepartment of Psychology, George Mason University, Fairfax, VA, United States of America.
Scott J CrowDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States of America; The Emily Program, St. Paul, MN, United States of America.
Carol B PetersonDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States of America; The Emily Program, St. Paul, MN, United States of America.

Funding

Regional Postdoctoral Training Grant in Eating Disorders ResearchT32MH082761 · NIMH · UNIVERSITY OF MINNESOTA · PI CAROL B. PETERSON · 2009 to 2026
$6.2M
Neural Correlates of Reward and Symptom Expression in Anorexia NervosaK23MH112867 · NIMH · UNIVERSITY OF MINNESOTA · PI HAYNOS, ANN FRANCES · 2017 to 2021
$878k
Affective and Neurocognitive Dimensions across Eating Disorder PsychopathologyK23MH101342 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LAVENDER, JASON MATTHEW · 2014 to 2018
$704k
NIMH NIH HHS K23 MH101342NIMH NIH HHS K23 MH112867NIMH NIH HHS T32 MH082761
6 · The paper itself

Abstract

Models of anorexia nervosa (AN) posit that symptoms are maintained through deficient reward and enhanced punishment processing. However, theoretical and empirical inconsistencies highlight the need for a more nuanced conceptualization of this literature. Our goal was to comprehensively review the research on reward and punishment responding in AN from a cue-specific lens to determine which stimuli evoke or discourage reward and punishment responses in this population, and, ultimately, what properties these rewarding and punishing cues might share. A systematic review interrogating reward and punishment responses to specific cues yielded articles (n = 92) that examined responses to disorder relevant (e.g., food) and irrelevant (e.g., money) stimuli across self-report, behavioral, and biological indices. Overall, in most studies individuals with AN exhibited aversive responses to cues signaling higher body weights, social contexts, and monetary losses, and appetitive responses to cues for weight loss behaviors and thinness. Findings were more mixed on responses to palatable food and monetary gains. Results highlight that reward and punishment responding in AN are context specific and may be affected by varied stimulus qualities (e.g., predictability, controllability, delay, effort). Increasing specificity in future research on reward and punishment mechanisms in AN will better inform development of precisely-targeted interventions.

Indexed as

CuesPunishmentRewardAnorexia NervosaHumansAnorexia nervosaAppetitiveAversiveEating disordersPunishmentReward

Identifiers

PMID32521390
PMCPMC7335637

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.