Evidence map›Paper›PMID 32521227›Full record

ArticleStructure (London, England : 1993)2020

Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.

Kang Zhou, Shiheng Liu, Nathan J Hardenbrook, Yanxiang Cui, Bryan A Krantz, Z Hong Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Structure (London, England : 1993), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Site-Specific Labeling andBiochemistry · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kang ZhouCalifornia NanoSystems Institute, University of California, Los Angeles, CA 90095, USA.
Shiheng LiuCalifornia NanoSystems Institute, University of California, Los Angeles, CA 90095, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.
Nathan J HardenbrookDepartment of Microbial Pathogenesis, University of Maryland, Baltimore, Baltimore, MD 21201, USA.
Yanxiang CuiCalifornia NanoSystems Institute, University of California, Los Angeles, CA 90095, USA.
Bryan A KrantzDepartment of Microbial Pathogenesis, University of Maryland, Baltimore, Baltimore, MD 21201, USA. Electronic address: bkrantz@umaryland.edu.
Z Hong ZhouCalifornia NanoSystems Institute, University of California, Los Angeles, CA 90095, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA. Electronic address: hong.zhou@ucla.edu.

Funding

Genome Structure, Transcription and Packaging of dsRNA VirusesR01AI094386 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Z Hong ZHOU · 2012 to 2026
$6.0M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
TRAINING PROGRAM IN INTEGRATIVE MEMBRANE BIOLOGYT32GM008181 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI RIZZO, MEGAN A, TRUDEAU, MATTHEW C · 1987 to 2022
$4.9M
In situ atomic structures of the Kaposi's sarcoma-associated herpesvirus portal-terminase complex and glycoproteinsR01DE025567 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING, ZHOU, Z HONG · 2016 to 2024
$4.0M
West/Midwest Consortium for High-Resolution Cryo Electron MicroscopyU24GM116792 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGBANDJE-MCKENNA, MAVIS, DOKLAND, TERJE · 2016 to 2020
$3.0M
HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
Molecular analyses of toxin nanopore structural dynamicsR21AI124020 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI GOODLETT, DAVID ROBINSON, KRANTZ, BRYAN ANDREW · 2016 to 2017
$437k
NCRR NIH HHS S10 RR023057NIAID NIH HHS R01 AI094386NIAID NIH HHS R21 AI124020NIDCR NIH HHS R01 DE025567NIGMS NIH HHS R01 GM071940NIGMS NIH HHS T32 GM008181NIGMS NIH HHS U24 GM116792NIH HHS S10 OD018111
6 · The paper itself

Abstract

Pathogenesis of anthrax disease involves two cytotoxic enzymes-edema factor (EF) and lethal factor (LF)-which are individually recruited by the protective antigen heptamer (PA

Indexed as

Antigens, BacterialBacterial ToxinsCryoelectron MicroscopyMolecular Docking SimulationMolecular Dynamics SimulationProtein Multimerizationanthrax toxinAntigens, BacterialBacterial Toxinsanthrax prechannelcomplex structurecryo-EMedema factorlethal factor

Identifiers

PMID32521227
PMCPMC7519843

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.