Evidence map›Paper›PMID 32521208›Full record

ArticleGut microbes2020

CEACAM1 regulates CD8

Julia Zöller, Jana-Fabienne Ebel, Vishal Khairnar, Verena Schmitt, Robert Klopfleisch, Jana Meiners, Virginia Seiffart, Wiebke Hansen, Jan Buer, Bernhard B Singer and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Elucidating the role of S100A10 in CD8Cell death & disease · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Julia ZöllerInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.ORCID 0000-0002-2121-2892
Jana-Fabienne EbelInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.ORCID 0000-0001-7954-3187
Vishal KhairnarInstitute for Immunology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.ORCID 0000-0002-3584-7530
Verena SchmittInstitute of Anatomy, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
Robert KlopfleischInstitute of Veterinary Pathology, Free University of Berlin , Berlin, Germany.
Jana MeinersInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
Virginia SeiffartInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
Wiebke HansenInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
Jan BuerInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
Bernhard B SingerInstitute of Anatomy, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.ORCID 0000-0002-2213-6000
Karl S LangInstitute for Immunology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
Astrid M WestendorfInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen , Essen, Germany.
University of Duisburg-Essen · DECity of Hope · USFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of gastrointestinal infections continues to increase, and infectious colitis contributes significantly to morbidity and mortality worldwide. Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) has been discovered to be strongly involved in the intestinal homeostasis. However, whether intestinal CEACAM1 expression has an impact on the control of infectious colitis remains elusive.

Indexed as

AnimalsCarcinoembryonic AntigenCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCitrobacter rodentiumColitisColonEnterobacteriaceae InfectionsFemaleHumansMaleMiceMice, Inbred C57BLMice, KnockoutCarcinoembryonic AntigenCeacam1 protein, mouseCD8 T cellsCEACAM1enteric infectioninfectious colitisinhibitory molecule

Identifiers

PMID32521208
PMCPMC7524155
OpenAlexW3033272377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.