ArticleJournal of glaucoma2020
A Topographic Comparison of OCT Minimum Rim Width (BMO-MRW) and Circumpapillary Retinal Nerve Fiber Layer (cRNFL) Thickness Measures in Eyes With or Suspected Glaucoma.
Article in Journal of glaucoma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Robustness of automated Bruch's membrane opening minimum rim width and retinal nerve fiber layer thickness without clinical disc margin adjustment in glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Diagnostic accuracy of Bruch's membrane opening minimum rim width for detecting glaucoma in Indian myopic eyes.Indian journal of ophthalmology · 2026Article
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- Retinal neurodegeneration, neuroretinal rim analysis and choroid thickness in pseudoexfoliation syndrome with spectral domain optical coherence tomography.Scientific reports · 2025Article
- Anatomical Features can Affect OCT Measures Used for Clinical Decisions and Clinical Trial Endpoints.Translational vision science & technology · 2024Article
- Changes of Optical Coherence Tomography Parameters after Cataract Surgery in Primary Open-Angle Glaucoma Eyes.Korean journal of ophthalmology : KJO · 2023Article
- Detection of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry.Translational vision science & technology · 2022Article
- The OCT RNFL Probability Map and Artifacts Resembling Glaucomatous Damage.Translational vision science & technology · 2022Article
- Changes of Neuroretinal Rim and Retinal Nerve Fiber Layer Thickness Assessed by Optical Coherence Tomography After Filtration Surgery in Glaucomatous Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Reasons why OCT Global Circumpapillary Retinal Nerve Fiber Layer Thickness is a Poor Measure of Glaucomatous Progression.Translational vision science & technology · 2020Article
- Sources of Discrepancy between Retinal Nerve Fiber Layer and Bruch's Membrane Opening-Minimum Rim Width Thickness in Eyes with Glaucoma.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
PRéCIS:: Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer (cRNFL) thickness measures may be improved by comparing probability levels and accounting for blood vessel locations. PURPOSE: To understand the differences between 2 optical coherence tomography measures of glaucomatous damage: the BMO-MRW and cRNFL thickness. MATERIALS AND
methodsOptical coherence tomography circle scans were obtained for an early glaucoma group (EG) of 88 eyes (88 patients) with 24-2 mean deviation better than -6.0 dB, and a broader group (BG) of 188 eyes (110 patients) with 24-2 mean deviation from -0.15 to -27.0 dB. On the basis of a commercial report, the cRNFL and BMO-MRW of each hemidisc was classified as abnormal if either of the 2 superior (inferior) sectors, temporal superior and nasal superior (temporal inferior and nasal inferior), was yellow or red (P<5%); and as normal if both were green (P≥5%). In addition, a post hoc analysis identified the reasons for disagreements on the basis of the presence (or absence) of glaucomatous damage at a hemidisc level (consensus of 4 experts).
resultsThe BMO-MRW and cRNFL measures agreed in 81.9% (broader group) and 73.9% (EG) of the hemidiscs. In both groups, an abnormal-BMO-MRW/normal-cRNFL disagreement was as common as a normal-BMO-MRW/abnormal-cRNFL. Of the 46 EG hemidisc disagreements, the number of "mistakes" for BMO-MRW (28) was nonsignificantly higher than for cRNFL (18) (P=0.15). Primary causes for disagreement were as follows: borderline significance level, a local defect, and aberrant blood vessel location.
conclusionsAlthough BMO-MRW and cRNFL measures agreed in the majority of hemidiscs, they still disagreed in over 25% of the EG hemidiscs. These measures may be improved by comparing actual probability levels and accounting for blood vessel locations. However, both can miss information available on retinal ganglion cell/retinal nerve fiber layer probability maps.
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