ArticleAmerican journal of physiology. Lung cellular and molecular physiology2020
Consideration of Pannexin 1 channels in COVID-19 pathology and treatment.
Abstract read
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Article in American journal of physiology. Lung cellular and molecular physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- The impact of Panx1 on inflammation, immunity, and cancer: a comprehensive review.Frontiers in medicine · 2025Review
- Pharmacological mechanisms of probenecid for SARS-CoV-2 and RSV co-infection: findings of system pharmacology, molecular docking, molecular dynamics simulation, and structure-activity relationship.Frontiers in microbiology · 2025Article
- Article
- Overlap in synaptic neurological condition susceptibility pathways and the neural pannexin 1 interactome revealed by bioinformatics analyses.Channels (Austin, Tex.) · 2023Article
- Article
- Review
- Effects of Drugs Formerly Suggested for COVID-19 Repurposing on Pannexin1 Channels.International journal of molecular sciences · 2022Article
- Possible role of pannexin 1 channels and purinergic receptors in the pathogenesis and mechanism of action of SARS-CoV-2 and therapeutic potential of targeting them in COVID-19.Life sciences · 2022Review
- Purinergic signaling elements are correlated with coagulation players in peripheral blood and leukocyte samples from COVID-19 patients.Journal of molecular medicine (Berlin, Germany) · 2022Article
- Repurposing Probenecid to Inhibit SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus (RSV) Replication.Viruses · 2022Review
- A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling.Purinergic signalling · 2022Review
- Role of CD39 in COVID-19 Severity: Dysregulation of Purinergic Signaling and Thromboinflammation.Frontiers in immunology · 2022Article
- Mechanisms of SARS-CoV-2 and Male Infertility: Could Connexin and Pannexin Play a Role?Frontiers in physiology · 2022Review
- The Potential of Purinergic Signaling to Thwart Viruses Including SARS-CoV-2.Frontiers in immunology · 2022Review
- Article
- Pannexin 1 as a driver of inflammation and ischemia-reperfusion injury.Purinergic signalling · 2021Review
- SARS-CoV-2 may trigger inflammasome and pyroptosis in the central nervous system: a mechanistic view of neurotropism.Inflammopharmacology · 2021Review
- SARS-CoV-2 early infection signature identified potential key infection mechanisms and drug targets.BMC genomics · 2021Article
- Is There an Effect of Fetal Mesenchymal Stem Cells in the Mother-Fetus Dyad in COVID-19 Pregnancies and Vertical Transmission?Frontiers in physiology · 2020Article
- The Role of Connexin 43 and Pannexin 1 During Acute Inflammation.Frontiers in physiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Leigh Anne SwayneDivision of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.ORCID 0000-0001-5852-3144
Scott R JohnstoneFralin Biomedical Research Institute at Virginia Tech Carilion Center for Heart and Reparative Medicine Research, Virginia Tech, Roanoke, Virginia.ORCID 0000-0003-1920-5033
Chen Seng NgDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Juan C Sanchez-AriasDivision of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.
Miranda E GoodMolecular Cardiology Research Institute, Tufts Medical Center, Boston, Massachusetts.
Silvia PenuelaDepartment of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada.
Alexander W LohmanDepartment of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada.
Abigail G WolpeRobert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
Victor E LaubachDepartment of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.ORCID 0000-0001-9673-5383
Michael KovalDepartment of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, Georgia.ORCID 0000-0002-5422-5614
Brant E IsaksonRobert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.ORCID 0000-0002-7692-6294
Funding
Role of Pannexins in Vascular Smooth Muscle CellsP01HL120840 · NHLBI · UNIVERSITY OF VIRGINIA · PI BAYLISS, DOUGLAS A., RAVICHANDRAN, KODI S · 2014 to 2023
$24.0MPurinergic Regulation of Veinous Endothelial PermeabilityR01HL137112 · NHLBI · UNIVERSITY OF VIRGINIA · PI Brant E Isakson, MICHAEL H. KOVAL · 2018 to 2026
$4.7MPannexin-1 Signaling in Lung Ischemia-Reperfusion InjuryR01HL133293 · NHLBI · UNIVERSITY OF VIRGINIA · PI LAUBACH, VICTOR E · 2017 to 2020
$2.3MAlcohol and the alveolar epithelial barrierR01AA025854 · NIAAA · EMORY UNIVERSITY · PI KOVAL, MICHAEL H. · 2017 to 2021
$1.9MVascular Pannexin 1 in Ischemic StrokeR00HL143165 · NHLBI · TUFTS MEDICAL CENTER · PI GOOD, MIRANDA E · 2020 to 2022
$747kCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (CANRIMT, NSERC) RGPIN-2017-03889Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de recherche en santé du Canada) MOP142215HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) HL120840HHS | NIH | National Heart, Lung, and Blood Institute (NHBLI) HL137112NHLBI NIH HHS P01 HL120840NHLBI NIH HHS R00 HL143165NHLBI NIH HHS R01 HL133293NHLBI NIH HHS R01 HL137112NIAAA NIH HHS R01 AA025854
Abstract
PubMed holds no abstract for this paper.
Indexed as
BetacoronavirusConnexinsCoronavirus InfectionsCOVID-19HumansNerve Tissue ProteinsPandemicsPneumonia, ViralSARS-CoV-2ConnexinsNerve Tissue ProteinsPANX1 protein, humanCOVID-19endotheliumPannexin 1SARS-CoV-2
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.