ArticleHuman brain mapping2020
Divergence between functional magnetic resonance imaging and clinical indicators of language dominance in preoperative language mapping.
Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Roles of fMRI and Wada tests in the presurgical evaluation of language functions in temporal lobe epilepsy.Frontiers in neurology · 2022Pooled it
- Discordant Wada and fMRI language lateralization: a case report.The Journal of international medical research · 2024Article
- Language Lateralization by Passive Auditory fMRI in Presurgical Assessment for Temporal Lobe Epilepsy: A Single-Center Retrospective Study.Journal of clinical medicine · 2024Article
- Bilateral and asymmetrical localization of language function identified by the superselective infusion of propofol in an epilepsy patient with a mild malformation of cortical development: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Surgical treatment of temporal lobe epilepsy: comparative results of selective amygdalohippocampectomy versus anterior temporal lobectomy from a referral center in Brazil.Arquivos de neuro-psiquiatria · 2023Article
- Divergence between functional magnetic resonance imaging and clinical indicators of language dominance in preoperative language mapping.Human brain mapping · 2020Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate determination of hemispheric language dominance prior to epilepsy surgery is critically important to minimize cognitive morbidity. Functional MRI (fMRI) is a noninvasive method that is highly concordant with other clinical indicators of language laterality, and is now commonly used to confirm language dominance. However, there is also a high frequency of divergence between fMRI findings and other clinical indices that complicate determination of dominance and surgical decision-making in individual patients. Despite this, divergent cases are rarely published or discussed. This article provides three illustrative examples to demonstrate common scenarios where fMRI may produce conflicting or otherwise difficult-to-interpret findings. We will also discuss potential reasons for divergence and propose a flow-chart to aid clinical decision making in such situations.
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