ArticleJournal of medical virology2020
Hyperpyrexia in patients with COVID-19.
Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Development and validation of a clinical and laboratory-based nomogram to predict mortality in patients with severe fever with thrombocytopenia syndrome.BMC infectious diseases · 2024Article
- Hyperpyrexia in a previously healthy pregnant female with COVID pneumonia: a case report and review of the literature.Journal of medical case reports · 2023Review
- Temperature management using an intervascular cooling device for a COVID-19 patient with refractory hyperthermia.Clinical case reports · 2023Article
- Research and Development of a COVID-19 Tracking System in Order to Implement Analytical Tools to Reduce the Infection Risk.Sensors (Basel, Switzerland) · 2022Article
- Risk factors for developing severe COVID-19 in China: an analysis of disease surveillance data.Infectious diseases of poverty · 2021Article
- Beneficial effects of dantrolene in the treatment of rhabdomyolysis as a potential late complication associated with COVID-19: a case report.European journal of medical research · 2021Article
- Higher Temperatures, Higher Solar Radiation, and Less Humidity Is Associated With Poor Clinical and Laboratory Outcomes in COVID-19 Patients.Frontiers in public health · 2021Article
- Hyperpyrexia and metabolic alkalosis in a COVID-19 patient.Journal of medical virology · 2021Article
- Hyperpyrexia in patients with COVID-19.Journal of medical virology · 2020Article
- Dexmedetomidine-Associated Hyperpyrexia in Three Critically Ill Patients With Coronavirus Disease 2019.Critical care explorations · 2020Article
- Tailor-Made Fluorinated Ionic Liquids for Protein Delivery.Nanomaterials (Basel, Switzerland) · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health emergency, in which its effective treatment and prevention remain obscured. Hyperpyrexia is an elevation of body temperature above 106.7°F (41.5°C) due to an abnormally increased hypothalamic-thermoregulatory set. The pathophysiology, impact, and outcomes of hyperpyrexia in patients with COVID-19 have not yet been studied. Herein, we present clinical features and outcomes of six patients with COVID-19 who had developed hyperpyrexia during hospitalization. All patients expired shortly after the onset of hyperpyrexia. Hyperpyrexia seems to adversely impact the outcomes and mortality in patients with COVID-19. The underlying mechanisms of developing hyperpyrexia in COVID-19 are mysterious. We propose it may be caused by SARS-CoV-2-related brain injury, exuberant immune response, and thrombus formation. More research is needed to verify our results. Understanding the association between hyperpyrexia and SARS-CoV-2 will help to elucidate the COVID-19 pathogenesis, which is mandatory for developing effective treatment strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.