Evidence map›Paper›PMID 32519555›Full record

ArticleJournal of the American Heart Association2020

Phenotyping Heart Failure According to the Longitudinal Ejection Fraction Change: Myocardial Strain, Predictors, and Outcomes.

Jin Joo Park, Alexandre Mebazaa, In-Chang Hwang, Jun-Bean Park, Jae-Hyeong Park, Goo-Yeong Cho

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03513653 (Strain for Risk Assessment and Therapeutic Strategies in Patients With Acute Heart Failure), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03513653 unknown statusnot on this map

Strain for Risk Assessment and Therapeutic Strategies in Patients With Acute Heart Failure (STRATS-AHF) Registry

TypeobservationalSponsorSeoul National University HospitalRan2009 to 2023Enrolled4,312ConditionsHeart Failure Acute, Heart Failure, EchocardiographyArmsEchocardiography with speckle-tracking imaging
3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  20. A Holistic View of Advanced Heart Failure.Life (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jin Joo ParkCardiovascular Center & Department of Internal Medicine Seoul National University Bundang Hospital Seongnam Korea.
Alexandre MebazaaDepartment of Anesthesiology and Intensive Care Medicine Hôpitaux Universitaires Saint Louis Lariboisière APHP University Paris Diderot UMR 942 Inserm Paris France.
In-Chang HwangCardiovascular Center & Department of Internal Medicine Seoul National University Bundang Hospital Seongnam Korea.
Jun-Bean ParkDepartment of Internal Medicine Seoul National University College of Medicine Seoul National University Hospital Seoul Korea.
Jae-Hyeong ParkDepartment of Internal Medicine Chungnam National University Hospital Daejeon Korea.
Goo-Yeong ChoCardiovascular Center & Department of Internal Medicine Seoul National University Bundang Hospital Seongnam Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Many patients with heart failure (HF) experience changes in left ventricular ejection fraction (LVEF) during follow-up. We sought to evaluate the predictors and outcomes of different HF phenotypes according to longitudinal changes in EF. Methods and Results A total of 2104 patients with acute HF underwent echocardiography at baseline and follow-up. Global longitudinal strain was measured at index admission. HF phenotypes were defined as persistent HF with reduced EF (persistent HFrEF, LVEF ≤40% at baseline and follow-up), heart failure with improved ejection fraction (LVEF≤40% at baseline and improved to >40% at follow-up), heart failure with declined ejection fraction (LVEF>40% at baseline and declined to ≤40% at follow up), and persistent HF with preserved EF (persistent HFpEF, LVEF>40% at baseline and follow-up). Overall, 1130 patients had HFrEF at baseline; during follow-up, 54.2% and 46.8% had persistent HFrEF and heart failure with improved ejection fraction, respectively. Among 975 patients with HFpEF at baseline, 89.5% and 10.5% had persistent HFpEF and heart failure with declined ejection fraction at follow-up, respectively. The 5-year all-cause mortality rates were 43.1%, 33.1%, 24%, and 17% for heart failure with declined ejection fraction, persistent HFrEF, persistent HFpEF, and heart failure with improved ejection fraction, respectively (global log-rank

Indexed as

Myocardial ContractionStroke VolumeVentricular Function, LeftAgedAged, 80 and overDisease ProgressionEchocardiographyFemaleHeart FailureHumansLongitudinal StudiesMaleMiddle AgedPhenotypePrognosisRepublic of Koreaejection fraction changeheart failureHFdEFHFiEFmyocardial strain

Identifiers

PMID32519555
PMCPMC7429069

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.