Evidence map›Paper›PMID 32519208›Full record

Trial reportThe Psychiatric quarterly2021

Assessment of Psychosocial Functioning in a Large Cohort of Patients with Schizophrenia.

C Kossmann, J Heller, M Brüne, C Schulz, M Heinze, J Cordes, B Mühlbauer, E Rüther, J Timm, G Gründer and 1 more

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Psychiatric quarterly, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

C KossmannDepartment of Psychiatry, Ruhr University Bochum, LWL University Hospital, Alexandrinenstr. 1-3, 44791, Bochum, Germany.
J HellerDepartment of Psychiatry, Ruhr University Bochum, LWL University Hospital, Alexandrinenstr. 1-3, 44791, Bochum, Germany.
M BrüneDepartment of Psychiatry, Ruhr University Bochum, LWL University Hospital, Alexandrinenstr. 1-3, 44791, Bochum, Germany.
C SchulzCompetence Centre for Clinical Trials - Biometry, University of Bremen, Bremen, Germany.
M HeinzeBrandenburg Medical School, University Clinic for Psychiatry and Psychotherapy, Immanuel Klinik Rüdersdorf, Rüdersdorf, Germany.
J CordesDepartment of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
B MühlbauerDepartment of Pharmacology, Klinikum Bremen Mitte, Bremen, Germany.
E RütherDepartment of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
J TimmCompetence Centre for Clinical Trials - Biometry, University of Bremen, Bremen, Germany.
G GründerDepartment of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
G JuckelDepartment of Psychiatry, Ruhr University Bochum, LWL University Hospital, Alexandrinenstr. 1-3, 44791, Bochum, Germany. georg.juckel@rub.de.ORCID http://orcid.org/0000-0001-9860-9620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study addresses the question of whether psychosocial functioning measured by the Personal and Social Performance (PSP) Scale is related to various psychopathological measures in a cohort of patients with schizophrenia.

methodsThe 'Neuroleptic Strategy Study' (NeSSy) performed at 14 German hospitals between 2010 and 2013 compared two treatment strategies instead of individual drugs. Secondary end-points were the two PSP scales as well as measures of quality of life (SF-36) and the Positive and Negative Syndrome Scale (PANSS).

results149 patients were randomised. There was no difference between the two treatment strategies (first-generation versus second-generation antipsychotics) with regard to the PSP. There were differences in doctors' assessments regarding psychosocial functioning compared with patients' own assessments. Furthermore, there were relationships between the PSP and quality of life, level of skills (ICF), and severity of disease (PANSS), level of sexual activities and poor well-being under antipsychotic medication but not with cognitive changes.

conclusionsThe findings on psychosocial functioning of patients with schizophrenia related to severity and skill level could be confirmed. Further findings were the correlation between psychosocial functioning and quality of life, well-being under treatment, and sexuality what emphasizes the substantial importance of a reduced psychosocial functioning.

Indexed as

Psychosocial FunctioningSchizophrenic PsychologyAdultAntipsychotic AgentsDouble-Blind MethodFemaleHumansMaleQuality of LifeSchizophreniaAntipsychotic AgentsPsychosocial functioningQuality of lifeRecoverySchizophrenia

Identifiers

PMID32519208
PMCPMC8918154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.