ReviewAnnals of surgical oncology2020
The Landmark Series: Management of Lateral Lymph Nodes in Locally Advanced Rectal Cancer.
Review in Annals of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for lateral pelvic lymph node metastasis in patients with lower rectal cancer: a systematic review and meta-analysis.Frontiers in oncology · 2023Pooled it
- Is Total Neoadjuvant Therapy the Solution to the Lateral Pelvic Lymph Nodes in Rectal Cancer? Retrospective Analysis From a High-Volume Tertiary Care Center.Annals of surgical oncology · 2026Article
- The significance of MRI-detected lateral lymph node metastasis in rectal cancer on local recurrence and survival-A nationwide cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Observational
- MRI-based scoring systems for selective lateral lymph node dissection in locally advanced low rectal cancer after neoadjuvant chemoradiotherapy.European radiology · 2025Article
- Operative Strategies for Beyond Total Mesorectal Excision Surgery for Rectal Cancer.Annals of surgical oncology · 2025Review
- Postoperative Morbidity and Factors Predicting the Development of Lymphoceles Following Lateral Pelvic Node Dissection for Rectal Cancer: A Cohort Study.Annals of surgical oncology · 2025Article
- ASO Author Reflections: Predictors of Pelvic Lymphocele Formation After Lateral Pelvic Node Dissection for Rectal Cancer.Annals of surgical oncology · 2025Article
- The Learning Curve for Robotic Lateral Pelvic Lymph Node Dissection for Rectal Cancer: A View From the West.Diseases of the colon and rectum · 2024Observational
- Identification of lateral pelvic nodes without metastasis in patients with rectal cancer treated with preoperative chemoradiotherapy or chemotherapy based on magnetic resonance imaging.Annals of gastroenterological surgery · 2024Article
- Management of internal iliac and obturator lymph nodes in mid-low rectal cancer.World journal of surgical oncology · 2024Review
- The current multidisciplinary management of rectal cancer.Annals of gastroenterological surgery · 2024Review
- Lateral lymph node dissection can increase overall survival and 5‑year survival rate of rectal cancer patients: A meta‑analysis.Oncology letters · 2024Article
- Current perspectives on the management of lateral pelvic lymph nodes in rectal cancer.World journal of clinical oncology · 2023Review
- Clinical significance of metastatic tumor deposit foci in rectal cancer in the lateral pelvic lymph node area.International journal of clinical oncology · 2023Article
- Evaluation of National Surgical Practice for Lateral Lymph Nodes in Rectal Cancer in an Untrained Setting.Annals of surgical oncology · 2023Article
- Therapeutic lateral pelvic lymph node dissection in rectal cancer: when to dissect? Size is not everything.The British journal of surgery · 2023Article
- High ligation versus low ligation of the inferior mesenteric artery in laparoscopic rectal cancer surgery: a retrospective study on surgical and long-term outcome.Langenbeck's archives of surgery · 2023Article
- Retrospective evaluation of national MRI reporting quality for lateral lymph nodes in rectal cancer patients and concordance with prospective re-evaluation following additional training.Insights into imaging · 2022Article
- ICG-Guided Lymphadenectomy during Surgery for Colon and Rectal Cancer-Interim Analysis of the GREENLIGHT Trial.Biomedicines · 2022Article
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has historically been a significant divide in the approach to the management of lateral pelvic lymph nodes in patients with rectal cancer. These differing paradigms have developed based upon competing priorities. In the West, the circumferential resection margin has been the main focus because it is a strong predictor of local recurrence, distal recurrence, and survival. This approach was supplemented by radiation and chemotherapy to treat the lateral pelvic lymph nodes and micrometastatic disease. In the East, lateral pelvic lymph nodes are considered to be locoregional; thus, surgical treatment has traditionally included routine dissection of this compartment for low rectal cancers without the use of neoadjuvant chemoradiotherapy. However, neither approach has adequately addressed the important issue of lateral compartment recurrence in patients with clinically evident lateral pelvic lymph node metastasis. The aims of the review were to present the recent key studies and evolution of lateral pelvic lymph node management in locally advanced rectal cancer and secondly to propose a management strategy for the lateral compartment based on the current evidence.
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Registered trials
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