SynthesisEuropean radiology2020
CT-guided radiofrequency ablation for osteoid osteomas: a systematic review.
Synthesis in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Robot-assisted targeting for osteoid osteoma: a systematic review.Journal of robotic surgery · 2026Pooled it
- High-intensity focused ultrasound-a needleless management for osteoid osteoma: a systematic review.Musculoskeletal surgery · 2024Pooled it
- Osteoid osteoma of the femoral neck as a rare cause of hip pain in a 50-year-old male: A case report.Radiology case reports · 2026Article
- Osteoid osteoma of the talus adjacent to the subtalar joint: a rare location and diagnostic challenge.International journal of surgery case reports · 2026Article
- Osteoid osteoma: topographical distribution and imaging features in children and adults.La Radiologia medica · 2026Article
- Clinical Application of an Ultrasonic Bone Scalpel in the Treatment of Osteoid Osteoma: A Single-Center Pilot Study.The Journal of bone and joint surgery. American volume · 2026Article
- CT-guided radiofrequency ablation in the treatment of pediatric and adult osteoid osteoma: single center experience and comparative results.Skeletal radiology · 2026Article
- Osteoid Osteoma of the Calcaneus and Patella: A Report of Two Cases and Review of the Literature.Cureus · 2026Article
- Robot-assisted radiofrequency ablation versus open resection for osteoid osteoma: an analysis of perioperative outcomes and a rare case of malignant transformation.Frontiers in oncology · 2026Article
- An analysis of the imaging features and diagnostic value of osteoid osteoma on DR, CT, and MRI.Frontiers in medicine · 2026Article
- Cone beam computed tomography navigation reduces impact of poor prognostic factors in osteoid osteoma radiofrequency ablation.Journal of clinical orthopaedics and trauma · 2025Article
- Long-term results of CT-guided radiofrequency ablation therapy in patients with osteoid osteoma : retrospective outcome analysis.Bone & joint open · 2025Article
- Computer-navigated, stereotactic navigation for percutaneous radiofrequency ablation of osteoid osteomas: dose comparison and procedure times.BMC musculoskeletal disorders · 2025Article
- Elongated morphology of osteoid osteoma is associated with radiofrequency ablation failure in children.Skeletal radiology · 2025Article
- To biopsy or not to biopsy: a retrospective review of presumed osteoid osteomas treated by radiofrequency ablation.European radiology · 2025Article
- Radiofrequency ablation of osteoid osteoma at the base of the coracoid process: Report of two cases.Clinical case reports · 2024Article
- Application of microwave ablation assisted degradation therapy in surgical treatment of intramedullary chondrosarcoma of extremities.World journal of surgical oncology · 2024Article
- A comparative study assessing the efficacy and safety of radiofrequency ablation versus surgical treatment for osteoid osteoma: retrospective analysis in a single institution.Insights into imaging · 2024Article
- Intra-articular Osteoid Osteoma of the Intermediate Cuneiform Bone Causing Articular Degeneration: A Rare Case and Literature Review.Orthopaedic surgery · 2023Review
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesCT-guided radiofrequency ablation (CT-RFA) is considered to be the gold standard for treatment of osteoid osteoma (OO) yet treatment failures (TFs) continue to be reported. This systematic review was conducted to evaluate factors associated with TF, such as ablation time, lesion location, and patient age as well as evaluating how TF has trended over time.
methodsOriginal studies reporting on patients undergoing CT-RFA of OO published between 2002 and 2019 were identified. TF was defined as patients with (1) recurrent or persistent pain +/- (2) imaging evidence of persistent OO. TFs were subdivided into those occurring after the index procedure (primary TF) or those occurring after repeat RFA (secondary TF). Subgroup analysis was performed for TF based on the study date (2002-2010 or 2010-2019), time duration of ablation at 90 °C (6 min or > 6 min), patient age, and tumor location (spinal vs. appendicular).
resultsSixty-nine studies were included for a total of 3023 patients. The global primary TF rate was 8.3% whereas the secondary TF rate was 3.1%. The TF rate reported in studies published after 2011(7%) was about half that during the earlier time period 2002-2010 (14%). There was no statistical difference in TF corrected for age, OO location, or duration of ablation (respectively p = 0.39, 0.13, and 0.23). The global complication rate was 3%, the most frequent being skin burns (n = 24; 0.7%).
conclusionsA decrease in TF observed between 2011-2019 compared to 2002-2010 may reflect improvements in operator technique or advancements in equipment. Duration of ablation, patient age, or location of OO failed to significantly correlate with TF. KEY POINTS: • CT-guided radiofrequency ablation of osteoid osteomas is a safe technique with a low rate of treatment failure (8.3% failure rate after the primary radiofrequency reducing to 3.1% following a secondary treatment). • The treatment failure rate has decreased over time, possibly due to an improved understanding of the disease process, better technique, and advances in equipment. • Duration of ablation, patient age, or lesion location did not significantly correlate with treatment failure.
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Registered trials
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