Evidence map›Paper›PMID 32518894›Full record

ArticleTherapeutic advances in ophthalmology

Shorya Vardhan Azad, Vinod Kumar, Rohan Chawla, Bibhuti Kashyap, Shreyas Temkar, Atul Kumar, Pradeep Venkatesh, Rajpal Vohra, Kabiruddin Molla, Anu Sharma

Open access · diamondAbstract read
In one paragraph

Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. The role of choriocapillaris vessel density in the pathogenesis of macular neovascularization associated with choroidal osteoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Trial
  2. Novel OCT findings in choroidal osteoma: brief report.International journal of retina and vitreous · 2021
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shorya Vardhan AzadDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.ORCID https://orcid.org/0000-0002-8050-5812
Vinod KumarDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Rohan ChawlaDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi 110029, India.ORCID https://orcid.org/0000-0002-6791-4435
Bibhuti KashyapDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Shreyas TemkarDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Atul KumarDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Pradeep VenkateshDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Rajpal VohraDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Kabiruddin MollaDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
Anu SharmaDr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.
All India Institute of Medical Sciences Raipur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study tumor characteristics of choroidal osteoma by swept source optical coherence tomography.

methodsA retrospective case series done at tertiary referral center in northern India. All patients diagnosed with choroidal osteoma examined on swept source optical coherence tomography were included. Swept source optical coherence tomography images were analyzed for integrity of retinal layers-intraretinal layers, outer retinal layers (photoreceptor), retinal pigment epithelium, and contour abnormalities. Choroidal changes assessed were tumor attributes such as shape, depth of choroidal involvement, tumor mass reflectivity pattern, tumor vascularity, and evolutionary structural abnormalities such as deossification, focal depressions, or choroidal neovascular membrane.

resultsA total of 15 eyes of 11 patients were analyzed. Seven of 11 patients were females. Mean age of presentation was approximately 26 years. Tumor was large in nine cases (>7.5 mm). Deossification was seen in 12 eyes. Inner and outer retinal integrity was maintained in 7 and 2 eyes, respectively. Most common internal tumor reflectivity pattern seen was a lamellar appearance (12/15). Increased signal transmission to choroid and focal area of deep excavation was present in 11 and 4 eyes, respectively. Osteoclastic activity was noted in 12 eyes. Choroidal neovascular membrane was seen in 6 eyes. Small lesions showed lamellar pattern of tumor reflectivity with preservation of retinal pigment epithelium and overlying retina. Larger tumors were deossified with 6 irregular tumor contour, disorganization of the outer retina, increased signal transmission to choroid, and areas of osteoclastic activity.

conclusionSwept source optical coherence tomography was helpful in assessing tumor attributes and predicting the different timelines in tumor evolution.

Indexed as

choroidal neovascular membrane osteomachoroidal osteomadeossified choroidal osteomaswept source optical coherence tomography

Identifiers

PMID32518894
PMCPMC7252358
OpenAlexW3032808880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.