Evidence map›Paper›PMID 32518871›Full record

ArticleKidney international reports2020

Lijun Ma, Hannah C Ainsworth, James A Snipes, Mariana Murea, Young A Choi, Carl D Langefeld, John S Parks, Manish S Bharadwaj, Jeff W Chou, Ashok K Hemal and 10 more

Open access · greenAbstract read
In one paragraph

Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Molecular Mechanisms of APOL1-Associated Kidney Disease.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. The Janus-faced functions of Apolipoproteins L in membrane dynamics.Cellular and molecular life sciences : CMLS · 2024
    Article
  14. Article
  15. Novel Therapies inKidney international reports · 2023
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. GWAS in Mice Maps Susceptibility to HIV-Associated Nephropathy to theJournal of the American Society of Nephrology : JASN · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 2 countries.

Lijun MaDepartment of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Hannah C AinsworthDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
James A SnipesDepartment of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Mariana MureaDepartment of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Young A ChoiDepartment of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Carl D LangefeldDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
John S ParksDepartment of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Manish S BharadwajDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Jeff W ChouDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Ashok K HemalDepartment of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Snezana PetrovicDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Ann L CraddockDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Dongmei ChengDepartment of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Gregory A HawkinsDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Lance D MillerDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Pamela J HicksDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Moin A SaleemChildren's Renal Unit, Bristol Royal Hospital for Children, University of Bristol, Bristol, United Kingdom.
Jasmin DiversDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Anthony J A MolinaDepartment of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Barry I FreedmanDepartment of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Wake Forest University · USBristol Royal Hospital for Children · GB

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Genetic Analysis of African American Hypertensive End-Stage Renal DiseaseR01DK070941 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FREEDMAN, BARRY IRA · 2006 to 2015
$4.7M
The Role of Hepatocyte ABCA1 in Lipid Mobilization and TransportR01HL119962 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PARKS, JOHN S · 2013 to 2022
$3.9M
Natural History of MYH9-Associated NephropathyR01DK084149 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FREEDMAN, BARRY IRA · 2009 to 2012
$2.3M
Genetic Determinants of Renal Transplant Survival from African American DonorsR01MD009055 · NIMHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DIVERS, JASMIN · 2014 to 2018
$2.0M
NCI NIH HHS P30 CA012197NHLBI NIH HHS R01 HL119962NIDDK NIH HHS R01 DK070941NIDDK NIH HHS R01 DK084149NIMHD NIH HHS R01 MD009055
6 · The paper itself

Abstract

introduction

methodsA global gene expression analysis was performed in human primary renal tubule cell lines derived from 50 African American individuals. Follow-up gene knock out, cell-based rescue, and microscopy experiments were performed.

results

conclusionResults suggest the mitochondrial fusion/fission pathway may be a therapeutic target in

Indexed as

African AmericansAPOL1chronic kidney diseaseFSGSmitochondria

Identifiers

PMID32518871
PMCPMC7271005
OpenAlexW3015038300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.