Bilateral optic disc pits in a pediatric patient with Cobb syndrome.

Bethlehem Mekonnen, Quintin Richardson, Jonah M Bhisitkul, Mohammad Diab, Nailyn Rasool

Open access · goldAbstract readCase Reports

In one paragraph

Article in American journal of ophthalmology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 46% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bethlehem MekonnenDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

Quintin RichardsonDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

Jonah M BhisitkulDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

Mohammad DiabDepartment of Orthopedic Surgery, University of California San Francisco, San Francisco, CA, USA.

Nailyn RasoolDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe a patient with Cobb Syndrome, a rare congenital disorder characterized by cutaneous and spinal arteriovenous malformations, who was found to have bilateral optic nerve pits. OBSERVATIONS: A 15-year-old boy diagnosed with Cobb Syndrome, manifesting as a large cutaneous port-wine stain associated with an underlying left paraspinous arteriovenous malformation resulting in severe scoliosis, presented for a screening ophthalmological exam. The patient had no visual symptoms. On examination, his visual acuity was 20/20 in each eye; however, bilateral optic disc pits were discovered on biomicroscopy and confirmed by spectral-domain optical coherence tomography. CONCLUSION AND IMPORTANCE: The unusual finding of bilateral optic disc pits in this rare congenital neurocutaneous disorder represents the first report of ophthalmic abnormalities in association with Cobb syndrome. Patients with Cobb Syndrome may be considered for screening ophthalmological exam for the detection of subclinical optic nerve abnormalities.

Indexed as

Arteriovenous malformationCavitary disc anomalyCobb syndromeCongenital optic disc anomalyOptic disc pitScoliosisSpectral-domain optical coherence tomography

Identifiers

PMID32518855

DOI10.1016/j.ajoc.2020.100749

PMCPMC7270543

OpenAlexW3024614472

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.