Evidence map›Paper›PMID 32518694›Full record

ArticleJournal of advanced research2020

Modulation of proteomic and inflammatory signals by Bradykinin in podocytes.

Richard Saoud, Miran A Jaffa, Aida Habib, Jingfu Zhao, Moustafa Al Hariri, Rui Zhu, Anwarul Hasan, Fuad N Ziyadeh, Firas Kobeissy, Yehia Mechref and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Bradykinin Type 2 Receptor Deficiency Reshapes Acute Neuroinflammation and Improves Cell Survival after Ischemic Stroke in Diabetic Mice.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. A modular map of Bradykinin-mediated inflammatory signaling network.Journal of cell communication and signaling · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Richard SaoudDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Lebanon.
Miran A JaffaEpidemiology and Population Health Department, Faculty of Health Sciences, American University of Beirut, Lebanon.
Aida HabibDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Lebanon.
Jingfu ZhaoDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, United States.
Moustafa Al HaririDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Lebanon.
Rui ZhuDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, United States.
Anwarul HasanDepartment of Mechanical and Industrial Engineering, Qatar University, Qatar.
Fuad N ZiyadehDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Lebanon.
Firas KobeissyDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Lebanon.
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, United States.
Ayad A JaffaDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Lebanon.
American University of Beirut · LBTexas Tech University · USInserm · FRQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic kidney disease. Here, we evaluated the temporal changes in proteome profile and inflammatory signals of podocytes in response to BK (10

Indexed as

Bradykinin 2 receptorCyclooxygenase-2ERK1/2Liquid Chromatography Mass SpectrometryPodocyte proteome

Identifiers

PMID32518694
PMCPMC7270529
OpenAlexW3029636796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.