Evidence map›Paper›PMID 32518631›Full record

ReviewF1000Research2020

Recent advances in understanding the neonatal microbiome.

Matthew J Dalby, Lindsay J Hall

Abstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. The role of Klebsiella populations in preterm infants.Biochemical Society transactions · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew J Dalby *Gut Microbes and Health, Quadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Lindsay J Hall *Gut Microbes and Health, Quadram Institute Bioscience, Norwich Research Park, Norwich, UK.ORCID 0000-0001-8938-5709

Funding

Biotechnology and Biological Sciences Research Council BB/R012490/1Biotechnology and Biological Sciences Research Council BBS/E/F/00044409Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10356Wellcome TrustWellcome Trust 100/974/C/13/Z
6 · The paper itself

Abstract

The neonatal developmental window represents a key time for establishment of the gut microbiota. First contact with these microbes within the infant gastrointestinal tract signifies the start of a critical mutualistic relationship, which is central for short- and longer-term health. Recent research has provided insights into the origin of these microbial pioneers, how they are maintained within the gut environment, and how factors such as antibiotics or preterm birth may disrupt the succession of beneficial microbes.  The acquisition, colonisation, and maintenance of the early life microbiota, and subsequent interactions with the host is a rapidly developing research area. In this review we explore some of these key topics which have been illuminated by recent research, and we highlight some of the important unresolved questions which currently limit our overall understanding of the neonatal gut microbiome.

Indexed as

Gastrointestinal MicrobiomeGastrointestinal TractAnti-Bacterial AgentsHumansInfantInfant, NewbornAnti-Bacterial Agentsantibioticsdietgutmicrobiomeneonatalpreterm infantstransmission

Identifiers

PMID32518631
PMCPMC7255898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.