Evidence map›Paper›PMID 32518604›Full record

ReviewExperimental and therapeutic medicine2020

Penile carcinoma and HPV infection (Review).

Lucian Iorga, Radu Dragos Marcu, Camelia Cristina Diaconu, Ana Maria Alexandra Stanescu, Anca Pantea Stoian, Dan Liviu Dorel Mischianu, Mihaela Surcel, Simona Bungau, Traian Constantin, Daniel Boda and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Prognostic value of the tumor immune microenvironment, PD-L1 and p16Virchows Archiv : an international journal of pathology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. The role and mechanism of human papillomavirus in urinary system tumors.The Journal of international medical research · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. HPV-related diseases in male patients: an underestimated conundrum.Journal of endocrinological investigation · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lucian IorgaUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Radu Dragos MarcuUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Camelia Cristina Diaconu'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Ana Maria Alexandra Stanescu'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Anca Pantea Stoian'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Dan Liviu Dorel MischianuUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Mihaela SurcelImmunology Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Simona BungauDepartment of Pharmacy, University of Oradea, 410073 Oradea, Romania.
Traian Constantin'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Daniel BodaDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Laszlo FeketeDermamed Private Clinic, 211 E60 Targu Mures, Romania.
Ovidiu Gabriel BratuUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul National Victor Babes · ROUniversity of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penile carcinoma is a relatively frequent health issue in the developing countries such as Africa, Asia and South America, usually affecting men aged between 50 and 70 years. It is a highly treatable disease in its early stages, but has serious physical and psychological consequences. Usually, penile carcinoma is located in the penile glans, in approximately half the cases, with the most frequent histological type being squamous cell carcinoma with its microscopic subtypes. A large number of risk factors have been reported for this disease, having a multifactorial etiology, HPV infection being one of the most important factors involved in its appearance. Out of the HPV DNA positive genital cancers HPV-16 is the most frequently found type in men, followed by HPV-18. The evolution of penile cancer includes two independent carcinogenic pathways, related or unrelated to HPV infection. There is limited data available in literature regarding HPV-related neoplasia, as well as on the efficacy of vaccination in men, with studies still ongoing.

Indexed as

HPV infectionpenile carcinomarisk factorssquamous cell carcinomavaccination

Identifiers

PMID32518604
PMCPMC7273896
OpenAlexW2986774224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.