Evidence map›Paper›PMID 32518541›Full record

ArticleCase reports in dermatology

Reflectance Confocal Microscopy of Pigmented Bowen's Disease: A Case Series of Difficult to Diagnose Lesions.

Sara Mazzilli, Reyes Gamo-Villegas, Ana Pampin-Franco, Jose Luis Lopez Estebaran, Fernando Pinedo, Laura Vollono, Monia Di Prete, Elena Campione, Salvador Gonzalez

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Bowen's Disease.Indian dermatology online journal
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sara MazzilliDepartment of Dermatology, Tor Vergata Hospital, Rome, Italy.
Reyes Gamo-VillegasDermatology Service, Fundation Alcorcon Hospital, Madrid, Spain.
Ana Pampin-FrancoDermatology Service, Fundation Alcorcon Hospital, Madrid, Spain.
Jose Luis Lopez EstebaranDermatology Service, Fundation Alcorcon Hospital, Madrid, Spain.
Fernando PinedoDepartment of Pathology, Fundation Alcorcon Hospital, Madrid, Spain.
Laura VollonoDepartment of Dermatology, Tor Vergata Hospital, Rome, Italy.
Monia Di PreteDepartment of Pathology, University of Rome Tor Vergata, Rome, Italy.
Elena CampioneDepartment of Dermatology, Tor Vergata Hospital, Rome, Italy.
Salvador GonzalezDepartment of Medicine and Medical Specialties, University of Alcalá, Madrid, Spain.
Hospital Universitario Fundación Alcorcón · ESUniversidad de Alcalá · ESUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigmented Bowen's disease is a rare variant of in situ squamous skin cell carcinoma. It mainly affects patients between 60 and 70 years of age. Its clinical features include well-demarcated, pigmented plaque arising in photo-exposed areas of the body. The best-characterized feature of the disease by histological examination is the presence of atypical keratinocytes, hyperpigmentation of the epidermis with trans-epidermal elimination of melanin and dermal melanophages. Precise diagnosis is often difficult, both clinically and dermoscopically, as Bowen's disease is often mistaken with keratinocyte tumors such as solar lentigines, seborrheic keratosis, Bowenoid papulosis, pigmented basal cell carcinoma, pigmented actinic keratosis; or even melanocytic lesions such as melanocytic nevus, pigmented epithelioid melanocytoma, and melanoma. Precise diagnosis often requires biopsy and histopathological examination of the tissue. Reflectance confocal microscopy is a noninvasive technique to diagnose pigmented skin lesions. To date, not much data are available regarding its use in the diagnosis of pigmented Bowen's disease. Herein, we report a well-represented case series of pigmented Bowen's disease imaged using dermoscopy and reflectance confocal microscopy.

Indexed as

Pigmented Bowen's diseaseReflectance confocal microscopySkin cancer

Identifiers

PMID32518541
PMCPMC7265740
OpenAlexW3025616263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.