ArticleHeredity2020
Evolution of multiple sex-chromosomes associated with dynamic genome reshuffling in Leptidea wood-white butterflies.
Article in Heredity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Molecular mechanisms of sex determination in Lepidoptera: current status and perspectives.Insect science · 2026Review
- A W chromosome-derived feminizing piRNA in pyralid moths demonstrates convergent evolution for primary sex determination signals in Lepidoptera.BMC biology · 2025Article
- Polyommatine Blue Butterflies Reveal Unexpected Integrity of the W Sex Chromosome Amid Extensive Chromosomal Fragmentation Linked to Telomere Restoration.Genome biology and evolution · 2025Article
- Sex-biased gene content is associated with sex chromosome turnover in Danaini butterflies.Molecular ecology · 2024Article
- The burst of satellite DNA in Leptidea wood white butterflies and their putative role in karyotype evolution.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024Article
- Zygosity-based sex determination in a butterfly drives hypervariability ofScience advances · 2024Article
- Genome-wide SNP analysis provides insights into the XX/XY sex-determination system in silver barb (Barbonymus gonionotus).Genomics & informatics · 2023Article
- Homeology of sex chromosomes in Amazonian Harttia armored catfishes supports the X-fission hypothesis for the XScientific reports · 2023Article
- Nascent evolution of recombination rate differences as a consequence of chromosomal rearrangements.PLoS genetics · 2023Article
- Chromosomal conservatism vs chromosomal megaevolution: enigma of karyotypic evolution in Lepidoptera.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- Chromosome-Level Assemblies of the Pieris mannii Butterfly Genome Suggest Z-Origin and Rapid Evolution of the W Chromosome.Genome biology and evolution · 2023Article
- High-density linkage maps and chromosome level genome assemblies unveil direction and frequency of extensive structural rearrangements in wood white butterflies (Leptidea spp.).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- Chromosome analysis and the occurrence of B chromosomes in fish parasite Acanthocephalus anguillae (Palaeacanthocephala: Echinorhynchida).Parasite (Paris, France) · 2023Article
- More hidden diversity in a cryptic species complex: a new subspecies ofComparative cytogenetics · 2023Article
- Chromosome-level genome and the identification of sex chromosomes in Uloborus diversus.GigaScience · 2022Article
- Article
- New insights into Xenopus sex chromosome genomics from the Marsabit clawed frog X. borealis.Journal of evolutionary biology · 2022Article
- Article
- Genome sequence and silkomics of the spindle ermine moth, Yponomeuta cagnagella, representing the early diverging lineage of the ditrysian Lepidoptera.Communications biology · 2022Article
- Evolution of sexual systems, sex chromosomes and sex-linked gene transcription in flatworms and roundworms.Nature communications · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
Sex-chromosome systems tend to be highly conserved and knowledge about their evolution typically comes from macroevolutionary inference. Rapidly evolving complex sex-chromosome systems represent a rare opportunity to study the mechanisms of sex-chromosome evolution at unprecedented resolution. Three cryptic species of wood-white butterflies-Leptidea juvernica, L. sinapis and L. reali-have each a unique set of multiple sex-chromosomes with 3-4 W and 3-4 Z chromosomes. Using a transcriptome-based microarray for comparative genomic hybridisation (CGH) and a library of bacterial artificial chromosome (BAC) clones, both developed in L. juvernica, we identified Z-linked Leptidea orthologs of Bombyx mori genes and mapped them by fluorescence in situ hybridisation (FISH) with BAC probes on multiple Z chromosomes. In all three species, we determined synteny blocks of autosomal origin and reconstructed the evolution of multiple sex-chromosomes. In addition, we identified W homologues of Z-linked orthologs and characterised their molecular differentiation. Our results suggest that the multiple sex-chromosome system evolved in a common ancestor as a result of dynamic genome reshuffling through repeated rearrangements between the sex chromosomes and autosomes, including translocations, fusions and fissions. Thus, the initial formation of neo-sex chromosomes could not have played a role in reproductive isolation between these Leptidea species. However, the subsequent species-specific fissions of several neo-sex chromosomes could have contributed to their reproductive isolation. Then, significantly increased numbers of Z-linked genes and independent neo-W chromosome degeneration could accelerate the accumulation of genetic incompatibilities between populations and promote their divergence resulting in speciation.
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