Evidence map›Paper›PMID 32518378›Full record

ArticleScientific reports2020

Age-independent increasing prevalence of Human Papillomavirus-driven oropharyngeal carcinomas in North-East Italy.

Annarosa Del Mistro, Helena Frayle, Anna Menegaldo, Niccolò Favaretto, Silvia Gori, Piero Nicolai, Giacomo Spinato, Salvatore Romeo, Giancarlo Tirelli, Maria Cristina da Mosto and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Papillomavirus Infection and Prevention: How Much Does the Sicilian Population Know? An Observational Study.International journal of environmental research and public health · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Annarosa Del MistroImmunology and Diagnostic Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Via Gattamelata, 64, 35128, Padova, Italy. annarosa.delmistro@iov.veneto.it.
Helena FrayleImmunology and Diagnostic Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Via Gattamelata, 64, 35128, Padova, Italy.
Anna MenegaldoDepartment of Neurosciences DNS, Section of Otolaryngology, University of Padova, P.le Ospedale 1, 31100, Treviso, Italy.
Niccolò FavarettoDepartment of Neurosciences DNS, Section of Otolaryngology, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.
Silvia GoriImmunology and Diagnostic Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Via Gattamelata, 64, 35128, Padova, Italy.
Piero NicolaiDepartment of Neurosciences DNS, Section of Otolaryngology, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.
Giacomo SpinatoDepartment of Neurosciences DNS, Section of Otolaryngology, University of Padova, P.le Ospedale 1, 31100, Treviso, Italy.
Salvatore RomeoAnatomical Pathology Unit, San Donà di Piave Hospital, Azienda ULSS 4 Veneto Orientale, Via Nazario Sauro 25, 30027, San Donà di Piave, VE, Italy.
Giancarlo TirelliHead and Neck Department, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.
Maria Cristina da MostoDepartment of Neurosciences DNS, Section of Otolaryngology, University of Padova, P.le Ospedale 1, 31100, Treviso, Italy.
Jerry PoleselUnit of Cancer Epidemiology, Aviano National Cancer Institute, IRCCS, Via Franco Gallini, 2, 33081, Aviano, PN, Italy.
Paolo Boscolo RizzoDepartment of Neurosciences DNS, Section of Otolaryngology, University of Padova, P.le Ospedale 1, 31100, Treviso, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HPV-driven oropharyngeal carcinomas (OPCs) show geographical variations with increasing temporal trends in several areas. We investigated their frequency and clinical outcomes within a prospective multicenter cohort study in North-East Italy. A tumor was defined as HPV-driven by using at least two different biomarkers, usually HPV-DNA positivity and p16

Indexed as

AdultAgedAged, 80 and overAge DistributionCyclin-Dependent Kinase Inhibitor p16FemaleHumansItalyMaleMiddle AgedOropharyngeal NeoplasmsPalatine TonsilPapillomaviridaePapillomavirus InfectionsPrevalenceViral LoadCyclin-Dependent Kinase Inhibitor p16

Identifiers

PMID32518378
PMCPMC7283341

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.