Evidence map›Paper›PMID 32518368›Full record

ArticleMucosal immunology2021

Long-term maintenance of lung resident memory T cells is mediated by persistent antigen.

Ida Uddbäck, Emily K Cartwright, Amalie S Schøller, Alexander N Wein, Sarah L Hayward, Jenna Lobby, Shiki Takamura, Allan R Thomsen, Jacob E Kohlmeier, Jan P Christensen

Open access · bronzeAbstract read
In one paragraph

Article in Mucosal immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Mucosal immunity and vaccine development.Signal transduction and targeted therapy · 2026
    Pooled it
  2. Review
  3. CD8MedComm · 2026
    Review
  4. Article
  5. CD27 and ICOS as Targets of PD-1/PD-L1 Signaling to Regulate Resident Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Ida Uddbäck *Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DK2200, Denmark.ORCID http://orcid.org/0000-0001-6007-5918
Emily K Cartwright *Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Amalie S SchøllerDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, DK2200, Denmark.
Alexander N WeinDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Sarah L HaywardDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Jenna LobbyDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Shiki TakamuraDepartment of Immunology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka, 589-8511, Japan.
Allan R ThomsenDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, DK2200, Denmark.
Jacob E KohlmeierDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA. jkohlmeier@emory.edu.
Jan P ChristensenDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, DK2200, Denmark. jpc@sund.ku.dk.
Emory University · USUniversity of Copenhagen · DKKindai University · JP

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Cellular and molecular programming of lung resident T cell memoryR35HL150803 · NHLBI · EMORY UNIVERSITY · PI JACOB E KOHLMEIER · 2020 to 2026
$5.4M
Imprinting of Lung-Resident T Cell MemoryR01HL122559 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2015 to 2019
$1.9M
Regulation of lung TRM maintenance and the decline of pulmonary cellular immunityR01HL138508 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2017 to 2019
$1.2M
Identifying mechanisms of lung tissue-resident memory CD8 T cell decayF31HL136101 · NHLBI · EMORY UNIVERSITY · PI HAYWARD, SARAH LOUISE · 2017 to 2019
$110k
NHLBI NIH HHS F31 HL136101NHLBI NIH HHS R01 HL122559NHLBI NIH HHS R01 HL138508NHLBI NIH HHS R35 HL150803NIAID NIH HHS HHSN272201300006CNIAID NIH HHS HHSN272201400004CNIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

Tissue-resident memory T cells (T

Indexed as

Immunologic MemoryAnimalsAntigensHost-Pathogen InteractionsImmunizationImmunomodulationInfluenza VaccinesLungLymphocyte CountMiceNucleocapsid ProteinsT-Lymphocyte SubsetsAntigensInfluenza VaccinesNucleocapsid Proteins

Identifiers

PMID32518368
PMCPMC7726002
OpenAlexW3033046187

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.