Evidence map›Paper›PMID 32518239›Full record

ArticleScientific reports2020

Lung Function and Gene Expression of Pathogen Recognition Pathway Receptors: the Cardia Lung Study.

Ramya Ramasubramanian, Ravi Kalhan, David R Jacobs, George R Washko, Lifang Hou, Myron D Gross, Weihua Guan, Bharat Thyagarajan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Identification of Metabolism-Associated Molecular Subtypes of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ramya RamasubramanianDivision of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-6710-909X
Ravi KalhanDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
David R JacobsDivision of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-7232-0543
George R WashkoDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Lifang HouDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Myron D GrossDepartment of Pathology and Laboratory Medicine, University of Minnesota School of Medicine, Minneapolis, MN, USA.
Weihua GuanDepartment of Biostatistics, University of Minnesota School of Public Health, Minneapolis, MN, USA.
Bharat ThyagarajanDepartment of Pathology and Laboratory Medicine, University of Minnesota School of Medicine, Minneapolis, MN, USA. thya0003@umn.edu.ORCID http://orcid.org/0000-0001-6968-6985
University of Minnesota · USNorthwestern University · USBrigham and Women's Hospital · US

Funding

Transitions from Impaired Respiratory Health to Lung DiseaseR01HL122477 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RAVI KALHAN · 2014 to 2026
$17.3M
NHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300028CNHLBI NIH HHS HHSN268201300029CNHLBI NIH HHS R01 HL122477
6 · The paper itself

Abstract

Activation of toll-like receptors (TLR1, TLR5, TLR6) and downstream markers (CCR1, MAPK14, ICAM1) leads to increased systemic inflammation. Our objective was to study the association between the gene expression levels of these six genes and lung function (Forced Expiratory Volume in one second (FEV

Indexed as

Gene Expression ProfilingAdultAgingBiomarkersFemaleHumansLungMaleReceptors, Cell SurfaceBiomarkersReceptors, Cell Surface

Identifiers

PMID32518239
PMCPMC7283270
OpenAlexW3033081416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.