ArticleNature communications2020
The genetic basis of sex determination in grapes.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 1 of them a synthesis that pooled it.
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Who cites it
116 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Plant sex chromosomes defy evolutionary models of expanding recombination suppression and genetic degeneration.Nature plants · 2021Pooled it
- Deciphering genetic basis of phenylethanoid glycoside production through integrative multiomics analysis inHorticulture research · 2026Article
- Automated Seed Morphometry Identifies Morphotypes Associated with Major Grapevine Haplotypic Lineages.Plants (Basel, Switzerland) · 2026Article
- Haplotype-resolved genome assembly of femaleHorticulture research · 2026Article
- Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Haplotype-resolved genome assembly of a male Dioscorea alata cultivar reveals the structure and evolution of young sex chromosomes.The Plant journal : for cell and molecular biology · 2026Article
- Haplotype-Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Integrated methylome and transcriptome analysis provides insight into DNA methylation-mediated networks in sexual dimorphism of Vernicia montana.BMC plant biology · 2026Article
- Dissecting the genetic architecture of early root-related traits in grapevine rootstocks across propagation methods and different scion.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Haplotype-resolved T2T gap-free genomes of the winegrape cultivar Cabernet Sauvignon.Scientific data · 2026Article
- Population structure of wild and cultivated grapevines in Armenia.BMC plant biology · 2026Article
- A complex reciprocal translocation is linked to reduced gamete viability in a loose-bunch grapevine somatic variant.BMC plant biology · 2026Article
- Unveiling the early defense response dynamics in grapevines against Plasmopara viticola by single-cell transcriptomics.Genome biology · 2026Article
- An advanced genotyping tool to inspect grapevine variability: the AxiomFrontiers in plant science · 2026Article
- Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado.bioRxiv : the preprint server for biology · 2025Article
- Dissection of the Ren6 and Ren7 powdery mildew resistance loci in Vitis piasezkii DVIT2027 using phased parental-progeny genomes and intraspecific locus graph reconstruction.G3 (Bethesda, Md.) · 2025Article
- Leveraging foundation models to dissect the genetic basis of cluster compactness and yield in grapevine.Scientific reports · 2025Article
- Analyses of contiguous reference genomes of Amaranthus tuberculatus highlight the landscape of the sex-associated region and PEBP gene family diversity.BMC genomics · 2025Article
- A haplotype-resolved chromatin landscape connects cis-regulatory variants to trait variation in Citrus.BMC genomics · 2025Article
- The genetic basis of microbiome recruitment in grapevine and its association with fermentative and pathogenic taxa.The New phytologist · 2025Article
56 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It remains a major challenge to identify the genes and mutations that lead to plant sexual differentiation. Here, we study the structure and evolution of the sex-determining region (SDR) in Vitis species. We report an improved, chromosome-scale Cabernet Sauvignon genome sequence and the phased assembly of nine wild and cultivated grape genomes. By resolving twenty Vitis SDR haplotypes, we compare male, female, and hermaphrodite haplotype structures and identify sex-linked regions. Coupled with gene expression data, we identify a candidate male-sterility mutation in the VviINP1 gene and potential female-sterility function associated with the transcription factor VviYABBY3. Our data suggest that dioecy has been lost during domestication through a rare recombination event between male and female haplotypes. This work significantly advances the understanding of the genetic basis of sex determination in Vitis and provides the information necessary to rapidly identify sex types in grape breeding programs.
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