Evidence map›Paper›PMID 32518190›Full record

ArticlemBio2020

The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans.

Linda C Horianopoulos, Guanggan Hu, Mélissa Caza, Kerstin Schmitt, Peter Overby, James D Johnson, Oliver Valerius, Gerhard H Braus, James W Kronstad

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Fluorescent organelle markers inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Measuring Stress Phenotypes in Cryptococcus neoformans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  11. Article
  12. Article
  13. Frontiers in physiology · 2023
    Article
  14. Article
  15. Article
  16. TheMicrobiology spectrum · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Chaperone Networks in Fungal Pathogens of Humans.Journal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Linda C HorianopoulosMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Guanggan HuMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Mélissa CazaMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Kerstin SchmittInstitut für Mikrobiologie & Genetik, Georg-August-Universität, Göttingen, Germany.
Peter OverbyDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
James D JohnsonDepartment of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Oliver ValeriusInstitut für Mikrobiologie & Genetik, Georg-August-Universität, Göttingen, Germany.
Gerhard H BrausInstitut für Mikrobiologie & Genetik, Georg-August-Universität, Göttingen, Germany.ORCID 0000-0002-3117-5626
James W KronstadMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada kronstad@msl.ubc.ca.ORCID 0000-0003-4240-6976
University of British Columbia · CAUniversity of Göttingen · DE

Funding

Comparative and functional genomics of C. neoformansR01AI053721 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI KRONSTAD, JAMES W · 2003 to 2024
$5.4M
CIHR MOP-13234NIAID NIH HHS R01 AI053721
6 · The paper itself

Abstract

The opportunistic fungal pathogen

Indexed as

AnimalsCryptococcosisCryptococcus neoformansFemaleFungal ProteinsMiceMice, Inbred BALB CMitochondriaMutationOxidation-ReductionVirulenceFungal Proteinsalternative oxidasecapsulecell wallcomplex IIIcryptococcosiselectron transport chainfungal pathogenesismouse modeloxygen consumption

Identifiers

PMID32518190
PMCPMC7373193
OpenAlexW3033652799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.