Evidence map›Paper›PMID 32518167›Full record

ArticleThe Journal of biological chemistry2020

Two bacterial glycosphingolipid synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide.

Nozomu Okino, Mengbai Li, Qingjun Qu, Tomoko Nakagawa, Yasuhiro Hayashi, Mitsufumi Matsumoto, Yohei Ishibashi, Makoto Ito

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Novel Genomes ofMicroorganisms · 2026
    Article
  5. Isolation and characterization ofFrontiers in microbiology · 2026
    Article
  6. Article
  7. Central Roles of Glucosylceramide in Driving Cancer Pathogenesis.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. mBio · 2024
    Article
  12. Review
  13. Article
  14. Characterization of a Glycolipid Synthase Producing α-Galactosylceramide inInternational journal of molecular sciences · 2022
    Article
  15. Dietary Sphingolipids Contribute to Health via Intestinal Maintenance.International journal of molecular sciences · 2021
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nozomu OkinoDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan nokino@agr.kyushu-u.ac.jp.ORCID 0000-0001-5718-2683
Mengbai LiDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Qingjun QuDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Tomoko NakagawaDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Yasuhiro HayashiDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Mitsufumi MatsumotoElectric Power Development Co., Ltd., Wakamatsu Institute, Wakamatsu-ku, Kitakyushu, Fukuoka, Japan.
Yohei IshibashiDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Makoto ItoDepartment of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Kyushu University · JPJ-Power (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial glycosphingolipids such as glucuronosylceramide and galactosylceramide have been identified as ligands for invariant natural killer T cells and play important roles in host defense. However, the glycosphingolipid synthases required for production of these ceramides have not been well-characterized. Here, we report the identification and characterization of glucuronosylceramide synthase (ceramide UDP-glucuronosyltransferase [Cer-GlcAT]) in Z

Indexed as

Bacterial ProteinsBacteroides fragilisGalactosylceramidesGalactosyltransferasesGlucuronosyltransferaseGlycosphingolipidsZymomonasalpha-galactosylceramideBacterial ProteinsGalactosylceramidesGalactosyltransferasesGlucuronosyltransferaseGlycosphingolipidsbacteriabacterial metabolismceramideglucuronosylceramideglycolipidglycosyltransferaseinnate immunityinvariant natural killer T cellssphingolipidα-galactosylceramide

Identifiers

PMID32518167
PMCPMC7397116
OpenAlexW3033987162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.