ArticleThe Journal of biological chemistry2020
The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice.
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Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
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Who cites it
45 citing papers in PubMed, 58 citations in OpenAlex.
- Adenine nucleotide translocase 2 (ANT2) deficiency reprograms ferroptosis in alveolar progenitor cells to promote emphysema.bioRxiv : the preprint server for biology · 2026Article
- SLC16A6 is a tyrosine transporter for the melanosome.bioRxiv : the preprint server for biology · 2026Article
- Ferroptosis in retinal pigment epithelial cells: Current status and future developments.Indian journal of ophthalmology · 2026Review
- SLC25A28 Ameliorates Hyperoxic Lung Injury by Improving Mitochondrial Oxidative Phosphorylation in Alveolar Epithelial Cells.International journal of molecular sciences · 2026Article
- Regulation of mitochondrial iron homeostasis in tumor cells.Molecular medicine (Cambridge, Mass.) · 2026Review
- Research Progress on Copper Metabolism, Cuprotosis, and Their Regulatory Mechanism in Tumor Diagnosis and Treatment.Cancer management and research · 2026Review
- SLC25A mitochondrial carriers as biomarkers and therapeutic targets of spaceflight-induced dysfunction: the ADP/ATP carrier (AAC3) as a structural case study.Journal of translational medicine · 2025Article
- Mitochondrial dysfunction: the hidden catalyst in chronic kidney disease progression.Renal failure · 2025Review
- Mitochondrial iron transport via MFRN1 is required for erythroid cell cycle progression.Blood advances · 2025Article
- Probabilistic-graph-based spatial context-aware framework for interpretable spatial omics denoising and augmentation.Briefings in bioinformatics · 2025Article
- Microglial SLC25A28 Knockout Mitigates Spinal Cord Injury in Mice by Inhibiting Heme Synthesis and Subsequent NOX2 Activation.CNS neuroscience & therapeutics · 2025Article
- FAM210B regulates iron homeostasis and sex-specific responses in stress erythropoiesis.Experimental hematology · 2025Article
- Molecular characterization underlying IFN-α2 treatment in polycythemia vera: a transcriptomic overview.Molecular and cellular biochemistry · 2025Article
- FAM210B Regulates Iron Homeostasis and Sex-Specific Responses in Stress Erythropoiesis.bioRxiv : the preprint server for biology · 2025Article
- Single-Cell Transcriptomic Analysis of the Potential Mechanisms of Follicular Development inInternational journal of molecular sciences · 2025Article
- The Role of Solute Carrier Family Transporters in Hepatic Steatosis and Hepatic Fibrosis.Journal of clinical and translational hepatology · 2025Review
- Cardiomyopathies and a brief insight into DOX-induced cardiomyopathy.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Review
- SLC25A33-mediated mitochondrial DNA synthesis plays a critical role in the inflammatory response of M1 macrophages by contributing to mitochondrial ROS and VDAC oligomerization.International journal of biological sciences · 2025Article
- Cellular Iron Homeostasis.Advances in experimental medicine and biology · 2025Review
- Mechanism of ferroptosis regulating ischemic stroke and pharmacologically inhibiting ferroptosis in treatment of ischemic stroke.CNS neuroscience & therapeutics · 2024Review
Corrections and comments
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Authors and funding
21 authors at 5 institutions in 2 countries.
Alexandra SeguinDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Xuan JiaDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Aubree M EarlDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Liangtao LiDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Jared WallaceDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Andong QiuColumbia University, New York, New York, USA.
Thomas BradleyDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Rishna ShresthaDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Marie-Bérengère TroadecUniversity Brest, Inserm, EFS, UMR 1078, GGB, F-29200, Brest, France.ORCID 0000-0003-2668-9670
Matt HockinDepartment of Human Genetics, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Simon TitenDepartment of Human Genetics, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Dave E WarnerDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
P Tom DowdleDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Martin E WohlfahrtClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Elaine HillasDepartment of General Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Matthew A FirpoDepartment of General Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0002-7983-3982
John D PhillipsDepartment of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
Jerry KaplanDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Barry H PawHarvard Medical School, Children's Hospital, Boston, Massachusetts, USA.
Jonathan BaraschColumbia University, New York, New York, USA.
Diane M WardDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA diane.mcveyward@path.utah.edu.
University of Utah · USFred Hutch Cancer Center · USColumbia University · USBoston Children's Hospital · USInserm · FR
Funding
TRANSCRIPTION FACTOR GATA-1 IN TERMINAL ERYTHROID DEVELOPMENTP01HL032262 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI ORKIN, STUART H · 1985 to 2021
$38.9MStem Cell and Transplantation BiologyU54DK106829 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DEREK L STIREWALT · 2015 to 2026
$9.1MProteomics CoreU54DK110858 · NIDDK · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Anna E Beaudin, JAMES Eric COX · 2016 to 2026
$8.6MIRON LIPOCALIN NGAL IN KIDNEY DISEASER01DK073462 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARASCH, JONATHAN M. · 2007 to 2015
$3.0MFrascati: mitochondrial transporter and erythropoiesisR01DK070838 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI PAW, BARRY H · 2007 to 2011
$1.8MIron Delivery in the Developing KidneyR01DK092684 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARASCH, JONATHAN M. · 2012 to 2016
$1.7MNHLBI NIH HHS P01 HL032262NIDDK NIH HHS R01 DK070838NIDDK NIH HHS R01 DK073462NIDDK NIH HHS R01 DK092684NIDDK NIH HHS U54 DK106829NIDDK NIH HHS U54 DK110858
Abstract
Mitochondrial iron import is essential for iron-sulfur cluster formation and heme biosynthesis. Two nuclear-encoded vertebrate mitochondrial high-affinity iron importers, mitoferrin1 (Mfrn1) and Mfrn2, have been identified in mammals. In mice, the gene encoding Mfrn1,
Indexed as
AnimalsCation Transport ProteinsCell ProliferationHomeostasisIronLiver RegenerationMaleMembrane Transport ProteinsMiceMice, Inbred C57BLMitochondria, LiverCation Transport ProteinsIronMembrane Transport Proteinsmitoferrin protein, mouseSlc25a28 protein, mousecell proliferationgene knockoutiron metabolismlivermembrane transportmetal homeostasismitochondriamitoferrin (Mfrn)Slc25a28solute carrier family 25 member 37 (Slc25a37)
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.