Evidence map›Paper›PMID 32518161›Full record

ArticleThe Journal of biological chemistry2020

Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish.

Liang Hu, Hongyan Li, Zhiping Chi, Jianbo He

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Analysis and identification of mMolecular therapy. Nucleic acids · 2022
    Article
  9. Alternative RNA Splicing in Fatty Liver Disease.Frontiers in endocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Liang HuInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing, China.
Hongyan LiInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing, China.
Zhiping ChiInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing, China.
Jianbo HeInstitute of Developmental Biology and Regenerative Medicine, Southwest University, Beibei, Chongqing, China hejianbo@swu.edu.cn.ORCID 0000-0002-2551-8186
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver organogenesis begins with hepatic precursors in the foregut endoderm, followed by hepatoblast specification, differentiation, outgrowth, and maturation for the formation of functional hepatocytes. Although several signaling pathways and critical factors that regulate liver specification, differentiation, and proliferation have been identified, little is known about how liver maturation is regulated. Here, we used a screen for mutations affecting liver development in zebrafish and identified a

Indexed as

Gene DeletionGene Expression Regulation, DevelopmentalAnimalsApoptosisCell DifferentiationCell ProliferationCRISPR-Cas SystemsHepatocytesLiverZebrafishgene regulationhepatocyte nuclear factor 4alpha (Hnf4a)liver maturationliver organogenesismTORC1post-transcriptional regulationRNA-binding motif protein 15 (Rbm15)RNA-binding proteinzebrafish hepatocyte nuclear factor 4 (HNF-4)

Identifiers

PMID32518161
PMCPMC7450140
OpenAlexW3033811193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.