ArticleThe Journal of biological chemistry2020
The J-elongated conformation of β
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Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
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Who cites it
25 citing papers in PubMed, 37 citations in OpenAlex.
- βCurrent opinion in immunology · 2026Review
- Molecular dynamics simulations of beta-2-glycoprotein 1 (β2GPI) reveal that post-translational modifications facilitate novel structures.Scientific reports · 2026Article
- Anti-β2GPI IgG display a broad reactivity against different β2GPI domains beyond domain 1: results from the APS ACTION and multi-center Italian cohorts.Frontiers in immunology · 2026Article
- Article
- The J-shape of β2GPI reveals a cryptic discontinuous epitope across domains I and II.Journal of structural biology: X · 2025Article
- Antiphospholipid Syndrome: An Antibody-Mediated Disease With Emerging Therapeutic Opportunities.Arthritis & rheumatology (Hoboken, N.J.) · 2025Review
- Understanding the structure of βBlood vessels, thrombosis & hemostasis · 2025Review
- Mechanism of antiphospholipid antibody-mediated thrombosis in antiphospholipid syndrome.Frontiers in immunology · 2025Review
- Article
- The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.iScience · 2024Article
- Atomistic characterization of β2-glycoprotein I domain V interaction with anionic membranes.Journal of thrombosis and haemostasis : JTH · 2024Article
- Rethinking antiphospholipid syndrome to guide future management and research.Nature reviews. Rheumatology · 2024Review
- The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.bioRxiv : the preprint server for biology · 2024Article
- Article
- Structural analyses of βJournal of thrombosis and haemostasis : JTH · 2023Article
- Article
- Interaction of the antiphospholipid syndrome autoantigen beta-2 glycoprotein I with DNA and neutrophil extracellular traps.Clinical immunology (Orlando, Fla.) · 2023Article
- Combined detection of anticardiolipin and anti-β2-glycoprotein 1 antibodies may predict pregnancy outcome.American journal of translational research · 2022Article
- Managing Antiphospholipid Syndrome in Children and Adolescents: Current and Future Prospects.Paediatric drugs · 2022Review
- Specific domain V reduction of beta-2-glycoprotein I induces protein flexibility and alters pathogenic antibody binding.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 2 countries.
Eliza RubenEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
William PlanerEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Mathivanan ChinnarajEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-7749-7364
Zhiwei ChenEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Xiaobing ZuoX-Ray Science Division, Argonne National Laboratory, Argonne, Illinois, USA.
Vittorio PengoThrombosis Research Laboratory, Department of Cardiac Thoracic and Vascular Sciences, and Public Health, University of Padova, Padova, Italy.
Vincenzo De FilippisDepartment of Pharmaceutical & Pharmacological Sciences, University of Padua, Padua, Italy.
Ravi K AlluriDepartment of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Keith R McCraeDepartment of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Paolo MacorDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Francesco TedescoIstituto Auxologico Italiano, IRCCS, Laboratory of Immuno-Rheumatology, Milan, Italy.ORCID 0000-0003-2462-0493
Nicola PozziEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA nicola.pozzi@health.slu.edu.ORCID 0000-0003-2309-7100
Saint Louis University · USCleveland Clinic · USUniversity of Padua · ITArgonne National Laboratory · USIRCCS Istituto Auxologico Italiano · ITUniversity of Trieste · IT
Funding
STUDIES ON THROMBIN ALLOSTERYR01HL049413 · NHLBI · WASHINGTON UNIVERSITY · PI Enrico Di Cera · 2000 to 2026
$9.6MStructural enzymology of factor V activationR01HL147821 · NHLBI · SAINT LOUIS UNIVERSITY · PI Enrico Di Cera · 2019 to 2026
$3.7MStructural enzymology of protein CR01HL139554 · NHLBI · SAINT LOUIS UNIVERSITY · PI DI CERA, ENRICO · 2018 to 2025
$3.7MStructural Studies of Beta-2 glycoprotein I in the Antiphospholipid SyndromeR01HL150146 · NHLBI · SAINT LOUIS UNIVERSITY · PI POZZI, NICOLA · 2020 to 2024
$2.0MBIOPHYSICAL STUDIES OF THROMBINR29HL049413 · NHLBI · WASHINGTON UNIVERSITY · PI DI CERA, ENRICO · 1995 to 1999
–NHLBI NIH HHS R01 HL049413NHLBI NIH HHS R01 HL139554NHLBI NIH HHS R01 HL147821NHLBI NIH HHS R01 HL150146NHLBI NIH HHS R29 HL049413
Abstract
β
Indexed as
Antiphospholipid SyndromeAnimalsAntibodies, Antiphospholipidbeta 2-Glycoprotein ICricetinaeHEK293 CellsHumansKineticsMutagenesisProtein DomainsAntibodies, Antiphospholipidbeta 2-Glycoprotein Iantiphospholipid syndromeautoimmune diseaseautoimmunitybeta-2 glycoprotein Icoagulationcomplement systemlipid–protein interactionprotein–protein interactionsingle-molecule biophysicsstructural biologystructure-functionthrombosisX-ray crystallography
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.