ArticleProceedings of the National Academy of Sciences of the United States of America2020
Cell-size regulation in budding yeast does not depend on linear accumulation of Whi5.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Single-cell imaging reveals a key role of Bck2 in yeast cell size adaptation to nutrient challenges.The Journal of cell biology · 2026Article
- 3D confinement physically regulates cell cycle progression in budding yeast.Nature communications · 2026Article
- A Fkh1/2 binding site array in the WHI5 promoter drives sub-scaling transcription.Cell reports · 2026Article
- Love-thy-neighbor: Neural networks for tracking and lineage tracing in budding yeast.bioRxiv : the preprint server for biology · 2026Article
- Love-thy-neighbor: neural networks for tracking and lineage tracing in budding yeast.Bioinformatics advances · 2026Article
- A Fkh1/2 binding site array in thebioRxiv : the preprint server for biology · 2025Article
- A growing problem: The many unsolved mysteries of cell growth.Molecular biology of the cell · 2025Review
- Omic AI reveals new autophagy regulators from the Atg1 interactome inFrontiers in cell and developmental biology · 2025Article
- The "weaken-fill-repair" model for cell budding: Linking cell wall biosynthesis with mechanics.iScience · 2024Article
- Eukaryotic cell size regulation and its implications for cellular function and dysfunction.Physiological reviews · 2024Review
- Modeling the START transition in the budding yeast cell cycle.PLoS computational biology · 2024Article
- The cell morphological diversity of Saccharomycotina yeasts.FEMS yeast research · 2024Article
- Cell cycle-linked vacuolar pH dynamics regulate amino acid homeostasis and cell growth.Nature metabolism · 2023Article
- Modelling how plant cell-cycle progression leads to cell size regulation.PLoS computational biology · 2023Article
- Cell region fingerprints enable highly precise single-cell tracking and lineage reconstruction.Nature methods · 2022Article
- Scaling of biosynthesis and metabolism with cell size.Molecular biology of the cell · 2022Article
- The G1/S repressor WHI5 is expressed at similar levels throughout the cell cycle.BMC research notes · 2022Article
- High-resolution mass measurements of single budding yeast reveal linear growth segments.Nature communications · 2022Article
- Mad3 modulates the GScience advances · 2022Article
- The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor.Molecular biology of the cell · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Cells must couple cell-cycle progress to their growth rate to restrict the spread of cell sizes present throughout a population. Linear, rather than exponential, accumulation of Whi5, was proposed to provide this coordination by causing a higher Whi5 concentration in cells born at a smaller size. We tested this model using the inducible
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.