Evidence map›Paper›PMID 32518061›Full record

ArticleGenetics2020

Sophie J Walton, Han Wang, Porfirio Quintero-Cadena, Alex Bateman, Paul W Sternberg

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sophie J WaltonDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125.ORCID 0000-0003-1320-1525
Han WangDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125.ORCID 0000-0002-1933-5762
Porfirio Quintero-CadenaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125.ORCID 0000-0003-0067-5844
Alex BatemanEuropean Molecular Biology Laboratory, European Bioinformatics Institute, (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.ORCID 0000-0002-6982-4660
Paul W SternbergDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125 pws@caltech.edu.ORCID 0000-0002-7699-0173
California Institute of Technology · USEuropean Bioinformatics Institute · GB

Funding

WormBase: a core data resource for C. elegans and other nematodesU24HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI TIM SCHEDL, PAUL Warren STERNBERG · 2018 to 2026
$18.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Enhancing the C. elegans animal resource through genome editingR24OD023041 · OD · UNIVERSITY OF MINNESOTA · PI ROUGVIE, ANN E., STERNBERG, PAUL WARREN · 2017 to 2024
$5.1M
TEMPORAL CONTROL OF DEVELOPMENT IN C ELEGANSR01GM050227 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ROUGVIE, ANN E. · 1997 to 2010
$2.5M
Mechanisms of Sleep Regulation and Function in C. elegansR00GM126137 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, HAN · 2020 to 2022
$744k
Mechanisms of Sleep Regulation and Function in C. elegansK99GM126137 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI WANG, HAN · 2017 to 2018
$177k
NHGRI NIH HHS U24 HG002223NIGMS NIH HHS K99 GM126137NIGMS NIH HHS R00 GM126137NIGMS NIH HHS R01 GM050227NIH HHS P40 OD010440NIH HHS R24 OD023041
6 · The paper itself

Abstract

To mitigate the deleterious effects of temperature increases on cellular organization and proteotoxicity, organisms have developed mechanisms to respond to heat stress. In eukaryotes, HSF1 is the master regulator of the heat shock transcriptional response, but the heat shock response pathway is not yet fully understood. From a forward genetic screen for suppressors of heat-shock-induced gene expression in

Indexed as

Gene Expression RegulationHeat-Shock ResponseLongevityAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsHeat-Shock ProteinsCaenorhabditis elegans ProteinsHeat-Shock ProteinsAF4/FMR2affl-1affl-2C. elegansheat shock response

Identifiers

PMID32518061
PMCPMC7404228
OpenAlexW3033660440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.